Analysis of human liver disease using a cluster of differentiation (CD) antibody microarray

• Published in: Liver international Vol. 32; no. 10; pp. 1527 - 1534
• Main Authors: Rahman, Wassim, Huang, Pauline, Belov, Larissa, Chrisp, Jeremy S., Christopherson, Richard I., Stapelberg, Peter M., Warner, Fiona J., George, Jacob, Bowen, David G., Strasser, Simone I., Koorey, David, Sharland, Alexandra F., McCaughan, Geoffrey W., Shackel, Nicholas A.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.11.2012
• Subjects: Adult; Aged; Aged, 80 and over; Algorithms; Antibodies - metabolism; Antigens, CD - metabolism; CD array; Cluster Analysis; Female; hepatitis C; Hepatitis C virus; Human immunodeficiency virus; Humans; Immunophenotyping - methods; Leukocytes - metabolism; liver disease; Liver Diseases - diagnosis; Male; Middle Aged; Principal Component Analysis; Protein Array Analysis - methods

Background A CD antibody microarray has been previously developed allowing semi‐quantitative identification of greater than 80 CD antigens on circulating leucocytes from peripheral blood samples. This assay, which uses a live cell‐capture technique, enables an extensive leucocyte immunophenotype det...