The Industrial Age of Biocatalytic Transamination

• Published in: European journal of organic chemistry Vol. 2015; no. 32; pp. 6965 - 6982
• Main Authors: Fuchs, Michael, Farnberger, Judith E., Kroutil, Wolfgang
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.11.2015; WILEY‐VCH Verlag; Wiley Subscription Services, Inc
• Subjects: Amines; Asymmetric synthesis; Biocatalysis; Enzyme catalysis; Microreview; Pharmaceutical industry; Transamination; Amines; Biocatalysis; Asymmetric synthesis; Enzyme catalysis; Transamination

During the last decade the use of ω‐transaminases has been identified as a very powerful method for the preparation of optically pure amines from the corresponding ketones. Their immense potential for the preparation of chiral amines, together with their ease of use in combination with existing bioc...