Translational applications of microRNAs in cancer, and therapeutic implications

• Published in: Non-coding RNA research Vol. 2; no. 3-4; pp. 143 - 150
• Main Authors: Kwok, Grace T., Zhao, Jing Ting, Weiss, Jocelyn, Mugridge, Nancy, Brahmbhatt, Himanshu, MacDiarmid, Jennifer A., Robinson, Bruce G., Sidhu, Stan B.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2017; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: Cancer; MicroRNAs; Rare cancers; Translational medicine; Rare cancers; MicroRNAs; Translational medicine; Cancer

The search for targeted novel therapies for cancer is ongoing. MicroRNAs (miRNAs) display a number of characteristics making them an attractive and realisable option. In this review, we explore these applications, ranging from diagnostics, prognostics, disease surveillance, to being a primary therap...