Cardiac Structure and Function Across the Spectrum of Aldosteronism: the Atherosclerosis Risk in Communities Study

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 79; no. 9; pp. 1984 - 1993
• Main Authors: Brown, Jenifer M., Wijkman, Magnus O., Claggett, Brian L., Shah, Amil M., Ballantyne, Christie M., Coresh, Josef, Grams, Morgan E., Wang, Zhiying, Yu, Bing, Boerwinkle, Eric, Vaidya, Anand, Solomon, Scott D.
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 01.09.2022
• Subjects: Aldosterone; Atherosclerosis - diagnosis; Atherosclerosis - epidemiology; Atherosclerosis - etiology; Atrial Fibrillation - complications; Heart Atria; Heart Failure - complications; Heart Failure - etiology; Humans; Hyperaldosteronism - complications; Hyperaldosteronism - epidemiology; Renin; heart failure; mineralocorticoids; aldosterone; renin; echocardiography

Aldosterone production and mineralocorticoid receptor activation are implicated in myocardial fibrosis and cardiovascular events. Cardiac structure and function were assessed in 4547 participants without prevalent heart failure (HF) in the ARIC study (Atherosclerosis Risk in Communities), with echoc...