Efficacy, safety and tolerability of fesoterodine for overactive bladder syndrome

• Published in: The Journal of urology Vol. 178; no. 6; p. 2488
• Main Authors: Nitti, Victor W, Dmochowski, Roger, Sand, Peter K, Forst, Hans-Theo, Haag-Molkenteller, Cornelia, Massow, Ute, Wang, Joseph, Brodsky, Marina, Bavendam, Tamara
• Format: Journal Article
• Language: English
• Published: United States 01.12.2007
• Subjects: Administration, Oral; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Maximum Tolerated Dose; Middle Aged; Multivariate Analysis; Muscarinic Antagonists - administration & dosage; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome; Urinary Bladder, Overactive - diagnosis; Urinary Bladder, Overactive - drug therapy; Urodynamics

We evaluated the efficacy, tolerability and safety of the new antimuscarinic agent fesoterodine relative to placebo for overactive bladder syndrome. This was a randomized, double-blind, placebo controlled, multicenter trial performed in the United States. Overall 836 subjects with urinary frequency,...