Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression - Wood, Christian M.; Wafford, Keith A.; McCarthy, Andrew P.; Hewes, Nicola; Shanks, Elaine; Lodge, David; Robinson, Emma S.J. (Neuropharmacology, 2018)
Keywords: Amino Acids - pharmacology; Amphetamine - antagonists & inhibitors; Amphetamine - pharmacology; Animals; Antipsychotic Agents - pharmacology; Bridged Bicyclo Compounds - pharmacology; Bridged Bicyclo Compounds, Heterocyclic - pharmacology; Cyclohexanes - pharmacology; Dose-Response Relationship, Drug; EEG; Excitatory Amino Acid Agonists - pharmacology; Gamma Rhythm - drug effects; Gamma Rhythm - physiology; Han Wistar; Hyperlocomotion; Locomotion - drug effects; Locomotion - physiology; Male; Metabotropic glutamate receptor; mGluR2; mGluR3; Motor Activity - drug effects; Motor Activity - physiology; Mutation; Phencyclidine - antagonists & inhibitors; Phencyclidine - pharmacology; Rats; Receptors, Metabotropic Glutamate - deficiency; Receptors, Metabotropic Glutamate - genetics; Receptors, Metabotropic Glutamate - physiology; Sleep; Sleep - drug effects; Sleep - physiology; Theta Rhythm - drug effects; Theta Rhythm - physiology; Wakefulness - drug effects; Wakefulness - physiology; HFO; Grm2; Sleep; EEG; mGluR2; Hyperlocomotion; Metabotropic glutamate receptor; Han Wistar; mGluR3