Dissociable effects of basolateral amygdala lesions on decision making biases in rats when loss or gain is emphasized

• Published in: Cognitive, affective, & behavioral neuroscience Vol. 14; no. 4; pp. 1184 - 1195
• Main Authors: Tremblay, Melanie, Cocker, Paul J., Hosking, Jay G., Zeeb, Fiona D., Rogers, Robert D., Winstanley, Catharine A.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.12.2014; Springer; Springer Nature B.V
• Subjects: Analysis of Variance; Anatomical correlates of behavior; Animals; Basolateral Nuclear Complex - injuries; Basolateral Nuclear Complex - pathology; Basolateral Nuclear Complex - physiology; Behavioral psychophysiology; Behavioral Science and Psychology; Bias; Biological and medical sciences; Brain Injuries - chemically induced; Brain Injuries - pathology; Brain Injuries - physiopathology; Cognition. Intelligence; Cognitive Psychology; Conditioning, Operant - physiology; Decision Making - physiology; Decision making. Choice; Disease Models, Animal; Exploratory Behavior; Fundamental and applied biological sciences. Psychology; Neurosciences; Psychology; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Quinolinic Acid - toxicity; Rats; Rats, Long-Evans; Reaction Time; Reward; Risk-Taking; Risk aversion; Prospect theory; Gambling; Framing effect; Reflection effect; Loss-chasing; Amygdala; Rat; Decision making; Rodentia; Central nervous system; Loss; Cognition; Basal ganglion; Experimental study; Gambling game; Encephalon; Vertebrata; Mammalia; Animal; Lesion; Amygdaloid nucleus; Gain

Individuals switch from risk seeking to risk aversion when mathematically identical options are described in terms of loss versus gains, as exemplified in the reflection and framing effects. Determining the neurobiology underlying such cognitive biases could inform our understanding of decision maki...