Echocardiographic reference ranges for normal left atrial function parameters: results from the EACVI NORRE study
To obtain the normal ranges for echocardiographic measurements of left atrial (LA) function from a large group of healthy volunteers accounting for age and gender. A total of 371 (median age 45 years) healthy subjects were enrolled at 22 collaborating institutions collaborating in the Normal Referen...
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| Published in | European heart journal cardiovascular imaging Vol. 19; no. 6; p. 630 |
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| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
01.06.2018
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| Subjects | |
| Online Access | Get more information |
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| Abstract | To obtain the normal ranges for echocardiographic measurements of left atrial (LA) function from a large group of healthy volunteers accounting for age and gender.
A total of 371 (median age 45 years) healthy subjects were enrolled at 22 collaborating institutions collaborating in the Normal Reference Ranges for Echocardiography (NORRE) study of the European Association of Cardiovascular Imaging (EACVI). Left atrial data sets were analysed with a vendor-independent software (VIS) package allowing homogeneous measurements irrespective of the echocardiographic equipment used to acquire data sets. The lowest expected values of LA function were 26.1%, 48.7%, and 41.4% for left atrial strain (LAS), 2D left atrial emptying fraction (LAEF), and 3D LAEF (reservoir function); 7.7%, 24.2%, and -0.53/s for LAS-active, LAEF-active, and LA strain rate during LA contraction (SRa) (pump function) and 12.0% and 21.6% for LAS-passive and LAEF-passive (conduit function). Left atrial reservoir and conduit function were decreased with age while pump function was increased. All indices of reservoir function and all LA strains had no difference in both gender and vendor. However, inter-vendor differences were observed in LA SRa despite the use of VIS.
The NORRE study provides contemporary, applicable echocardiographic reference ranges for LA function. Our data highlight the importance of age-specific reference values for LA functions. |
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| AbstractList | To obtain the normal ranges for echocardiographic measurements of left atrial (LA) function from a large group of healthy volunteers accounting for age and gender.
A total of 371 (median age 45 years) healthy subjects were enrolled at 22 collaborating institutions collaborating in the Normal Reference Ranges for Echocardiography (NORRE) study of the European Association of Cardiovascular Imaging (EACVI). Left atrial data sets were analysed with a vendor-independent software (VIS) package allowing homogeneous measurements irrespective of the echocardiographic equipment used to acquire data sets. The lowest expected values of LA function were 26.1%, 48.7%, and 41.4% for left atrial strain (LAS), 2D left atrial emptying fraction (LAEF), and 3D LAEF (reservoir function); 7.7%, 24.2%, and -0.53/s for LAS-active, LAEF-active, and LA strain rate during LA contraction (SRa) (pump function) and 12.0% and 21.6% for LAS-passive and LAEF-passive (conduit function). Left atrial reservoir and conduit function were decreased with age while pump function was increased. All indices of reservoir function and all LA strains had no difference in both gender and vendor. However, inter-vendor differences were observed in LA SRa despite the use of VIS.
The NORRE study provides contemporary, applicable echocardiographic reference ranges for LA function. Our data highlight the importance of age-specific reference values for LA functions. |
| Author | Athanassopoulos, George D Hagendorff, Andreas Lopez, Teresa Galderisi, Maurizio Penicka, Martin Cimino, Sara Cardim, Nuno Hristova, Krasimira Zamorano, Jose Luis Cosyns, Bernard Lancellotti, Patrizio Baroni, Monica Lang, Roberto M van de Veire, Nico Barone, Daniele Bernard, Anne Rodrigo Carbonero, Jose David Contu, Laura Sugimoto, Tadafumi Badano, Luigi P Calin, Andreea Ilardi, Federica Rosca, Monica Moonen, Marie Magne, Julien Galli, Elena Vinereanu, Dragos Kacharava, George de la Morena, Gonzalo Robinet, Sébastien Nchimi, Alain Ozyigit, Tolga Donal, Erwan Addetia, Karima Dulgheru, Raluca Popescu, Bogdan A Go, Yun Yun Caballero, Luis Von Bardeleben, Ralph Stephan Habib, Gilbert Marchetta, Stella Esposito, Roberta |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29529180$$D View this record in MEDLINE/PubMed |
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| ContentType | Journal Article |
| Contributor | de Diego, Jose Juan Gomez Hagendorff, Andreas Lopez, Teresa Athanassopoulos, George D Jose, Seena Padayattil Penicka, Martin Cardim, Nuno Hristova, Krasimira Zamorano, Jose Luis Lancellotti, Patrizio Rimbas, Roxana Baroni, Monica Lang, Roberto M van de Veire, Nico Barone, Daniele Bernard, Anne Kotrc, Martin Kou, Seisyou Mgaloblishvili, Zaza Sugimoto, Tadafumi Badano, Luigi P Akhaladze, Natela Ilardi, Federica Gonjilashvili, Natalia Salustri, Alessandro Vinereanu, Dragos de la Morena, Gonzalo Kacharava, George Ciobanu, Andrea Olivia Carbonero, Jose David Rodrigo Robinet, Sébastien Peluso, Diletta Nchimi, Alain González-Carrillo, Josefa Ozyigit, Tolga Addetia, Karima Dulgheru, Raluca Go, Yun Yun Popescu, Bogdan A Voigt, Jens-Uwe Oliva, María José Von Bardeleben, Ralph Stephan Kurashvili, Levan de Sutter, Johan Marchetta, Stella |
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| Snippet | To obtain the normal ranges for echocardiographic measurements of left atrial (LA) function from a large group of healthy volunteers accounting for age and... |
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| SubjectTerms | Adult Age Factors Atrial Function, Left - physiology Cohort Studies Echocardiography - methods Echocardiography, Three-Dimensional - methods Female Healthy Volunteers Heart Atria - diagnostic imaging Humans Image Processing, Computer-Assisted - methods Linear Models Male Middle Aged Multivariate Analysis Observer Variation Reference Standards Sex Factors Statistics, Nonparametric |
| Title | Echocardiographic reference ranges for normal left atrial function parameters: results from the EACVI NORRE study |
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