Combined Diffusion Tensor Imaging and Apparent Transverse Relaxation Rate Differentiate Parkinson Disease and Atypical Parkinsonism

• Published in: American journal of neuroradiology : AJNR Vol. 38; no. 5; pp. 966 - 972
• Main Authors: Du, G., Lewis, M.M., Kanekar, S., Sterling, N.W., He, L., Kong, L., Li, R., Huang, X.
• Format: Journal Article
• Language: English
• Published: United States American Society of Neuroradiology 01.05.2017
• Subjects: Adult Brain; Aged; Atrophy; Brain - diagnostic imaging; Cerebellum; Control methods; Diagnosis, Differential; Differential diagnosis; Diffusion rate; Diffusion Tensor Imaging - methods; Disease control; Female; Humans; Learning algorithms; Machine learning; Magnetic resonance imaging; Male; Mesencephalon; Middle Aged; Movement disorders; Neostriatum; Neurodegenerative diseases; Neuroimaging - methods; Nuclei; Paralysis; Parkinson's disease; Parkinsonian Disorders - diagnostic imaging; Patients; Progressive supranuclear palsy; Red nucleus; ROC Curve; Speech disorders; Subthalamic nucleus

Both diffusion tensor imaging and the apparent transverse relaxation rate have shown promise in differentiating Parkinson disease from atypical parkinsonism (particularly multiple system atrophy and progressive supranuclear palsy). The objective of the study was to assess the ability of DTI, the app...