Detection Methods and Clinical Applications of Circulating Tumor Cells in Breast Cancer

• Published in: Frontiers in oncology Vol. 11; p. 652253
• Main Authors: Zhang, Hongyi, Lin, Xiaoyan, Huang, Yuan, Wang, Minghong, Cen, Chunmei, Tang, Shasha, Dique, Marcia R., Cai, Lu, Luis, Manuel A., Smollar, Jillian, Wan, Yuan, Cai, Fengfeng
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 02.06.2021
• Subjects: breast cancer; clinical application; CTCs; detection methods; liquid biopsy; Oncology

Circulating Tumor Cells (CTCs) are cancer cells that split away from the primary tumor and appear in the circulatory system as singular units or clusters, which was first reported by Dr. Thomas Ashworth in 1869. CTCs migrate and implantation occurs at a new site, in a process commonly known as tumor...