Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification - Sager, Jennifer E.; Yu, Jingjing; Ragueneau-Majlessi, Isabelle; Isoherranen, Nina (Drug metabolism and disposition, 2015)
Keywords: Animals; Computer Simulation; Drug Interactions - physiology; Humans; Minireview; Models, Biological; Pharmaceutical Preparations - metabolism; Pharmacokinetics; CDER; FDA; PD; CHMP; IVIVE; DDI; EMA; IQ; PBPK; PK; AUC