Gut Microbiota-Derived Components and Metabolites in the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD)

• Published in: Nutrients Vol. 11; no. 8; p. 1712
• Main Authors: Ji, Yun, Yin, Yue, Li, Ziru, Zhang, Weizhen
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 25.07.2019; MDPI
• Subjects: Animals; bacteria; Bacteria - genetics; Bacteria - metabolism; bile acids; bioactive compounds; carotenoids; Disease Progression; DNA; Fatty liver; Gastrointestinal Microbiome; glycolipids; Gut microbiota; hepatocytes; homeostasis; Host-Pathogen Interactions; Humans; indoles; ingredients; intestinal microorganisms; Intestines - microbiology; lipid metabolism; lipopolysaccharides; liver; Liver - metabolism; Liver - pathology; metabolites; Microbiota; Non-alcoholic Fatty Liver Disease - diagnosis; Non-alcoholic Fatty Liver Disease - metabolism; Non-alcoholic Fatty Liver Disease - microbiology; peptidoglycans; phenolic compounds; portal vein; Review; short chain fatty acids; Signal Transduction; trimethylamine; metabolism; metabolite; liver disease; gut microbiota

Human gut microbiota has been increasingly recognized as a pivotal determinant of non-alcoholic fatty liver disease (NAFLD). Apart from the changes in the composition of gut microbiota, the components and metabolites derived from intestinal microbiota have emerged as key factors in modulating the pa...