Tau Pathology in Chronic Traumatic Encephalopathy and Alzheimer's Disease: Similarities and Differences

• Published in: Frontiers in neurology Vol. 10; p. 980
• Main Authors: Katsumoto, Atsuko, Takeuchi, Hideyuki, Tanaka, Fumiaki
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 10.09.2019
• Subjects: chronic traumatic encephalopathy; cis p-tau; Neurology; prion; tau; traumatic brain injury

Traumatic brain injury (TBI) has been associated with the development of Alzheimer's disease (AD) because these conditions share common pathological hallmarks: amyloid-β and hyperphosphorylated tau accumulation. However, given recent data it is uncertain if a history of TBI leads to the develop...