Zinc and Skin Disorders

• Published in: Nutrients Vol. 10; no. 2; p. 199
• Main Authors: Ogawa, Youichi, Kinoshita, Manao, Shimada, Shinji, Kawamura, Tatsuyoshi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.02.2018; MDPI
• Subjects: acrodermatitis; alopecia; biotin; Carrier Proteins - metabolism; Cation Transport Proteins - metabolism; Deficiency Diseases - etiology; Deficiency Diseases - metabolism; dermis; erythema; fibroblasts; Fibroblasts - metabolism; Humans; intestinal mucosa; keratinocytes; Keratinocytes - metabolism; mammary glands; Mutation; nutrient deficiencies; pellagra; Review; secretory granules; Skin; Skin - metabolism; Skin Diseases - etiology; Skin Diseases - metabolism; tissue repair; transporters; zinc; Zinc - deficiency; Zinc - metabolism; Langerhans cells; skin; nutrition; acrodermatitis enteropathica; ATP; zinc

The skin is the third most zinc (Zn)-abundant tissue in the body. The skin consists of the epidermis, dermis, and subcutaneous tissue, and each fraction is composed of various types of cells. Firstly, we review the physiological functions of Zn and Zn transporters in these cells. Several human disor...