A systematic assessment of statistics, risk factors, and underlying features involved in pancreatic cancer

• Published in: Cancer epidemiology Vol. 58; pp. 104 - 110
• Main Authors: Aier, Imlimaong, Semwal, Rahul, Sharma, Anju, Varadwaj, Pritish Kumar
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.02.2019; Elsevier Limited
• Subjects: Age; Alcohol; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biomarkers; Body mass index; Chemotherapy; Chemotherapy resistance; Conflicts of interest; Cyclin-dependent kinases; Diabetes; Diagnosis; Epidemiology; Genomics; Genomics - methods; Humans; Kinases; Metastasis; Molecular Targeted Therapy; Mortality; Nab paclitaxelin; Pancreatic cancer; Pancreatic Neoplasms - classification; Pancreatic Neoplasms - drug therapy; Pancreatic Neoplasms - genetics; Proteins; Risk Factors; Smoking; Stroma; Surgery; Survival rate; Biomarkers; Nab paclitaxelin; Chemotherapy resistance; Survival rate; Pancreatic cancer

•Pancreatic cancer has one of the lowest survival rates.•Early detection is almost impossible; late diagnosis is difficult to treat because of chemotherapy resistance.•Mutation of KRAS is not the only key driver for pancreatic cancer.•Best outcome may be through implementation of combination drug th...