Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming

• Published in: Frontiers in cell and developmental biology Vol. 8; p. 760
• Main Authors: Lai, Xiaowei, Li, Qian, Wu, Fang, Lin, Jiechun, Chen, Jiekai, Zheng, Hui, Guo, Lin
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 06.08.2020
• Subjects: cancer; Cell and Developmental Biology; EMT; energy metabolism; glycolysis; OXPHOS; reprogramming

Epithelial-mesenchymal transition (EMT) and its critical roles during cancer progression have long been recognized and extensively reviewed. Recent studies on the generation of induced pluripotent stem cells (iPSCs) have established the connections among EMT, energy metabolism, DNA methylation, and...