Age-Related Neurodegenerative Diseases: A Stem Cell’s Perspective

• Published in: Cells (Basel, Switzerland) Vol. 14; no. 5; p. 347
• Main Authors: Calvo, Belén, Schembri-Wismayer, Pierre, Durán-Alonso, María Beatriz
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.03.2025; MDPI
• Subjects: Age; Aging; Aging - pathology; Alzheimer's disease; Amyotrophic lateral sclerosis; Analysis; Animal cognition; Animals; Anxiety; Cell culture; cell models; Cognitive ability; Development and progression; Drug development; Enzymes; Homeostasis; Humans; Huntingtons disease; MicroRNAs; Nervous system diseases; neural stem cells; Neurodegeneration; Neurodegenerative diseases; Neurodegenerative Diseases - pathology; Neurodegenerative Diseases - therapy; neurodegenerative disorders; Neurogenesis; Neurons; Parkinson's disease; Peptides; pluripotent stem cells; Proteins; Review; Secretome; Stem cells; Stem Cells - metabolism; stem-cell-based therapy; neurogenesis; cell models; pluripotent stem cells; neurodegenerative disorders; stem-cell-based therapy; neural stem cells

Neurodegenerative diseases encompass a number of very heterogeneous disorders, primarily characterized by neuronal loss and a concomitant decline in neurological function. Examples of this type of clinical condition are Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease and Amyotrophic L...