HNF4α-Mediated LINC02560 Promotes Papillary Thyroid Carcinoma Progression by Targeting the miR-505-5p/PDE4C Axis - Su, Yongcheng; Xu, Beibei; Gao, Chunyi; Pei, Wenbin; Ma, Miaomiao; Zhang, Wenqing; Hu, Tianhui; Zhang, Fuxing; Zhang, Shaoliang (Biomolecules (Basel, Switzerland), 2025)
Keywords: AKT protein; Binding sites; Cell culture; Cell Line, Tumor; Cell Movement - genetics; Cell Proliferation - genetics; Cyclic Nucleotide Phosphodiesterases, Type 4 - genetics; Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism; Development and progression; Disease Progression; Enzymes; Epithelial-Mesenchymal Transition - genetics; Experiments; Female; Gene Expression Regulation, Neoplastic; Genetic aspects; growth and metastasis; Health aspects; Hepatocyte Nuclear Factor 4 - genetics; Hepatocyte Nuclear Factor 4 - metabolism; HNF4α; Humans; Laboratory animals; LINC02560; Male; Malignancy; Medical prognosis; Metabolism; Metastasis; MicroRNAs; MicroRNAs - genetics; MicroRNAs - metabolism; miR-505-5p; Papillary thyroid carcinoma; Pathogenesis; PDE4C; Phosphodiesterases; Physiological aspects; PTC; RNA; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; Signal Transduction; Therapeutic targets; Thyroid cancer; Thyroid Cancer, Papillary - genetics; Thyroid Cancer, Papillary - metabolism; Thyroid Cancer, Papillary - pathology; Thyroid Neoplasms - genetics; Thyroid Neoplasms - metabolism; Thyroid Neoplasms - pathology; Transcription factors; Transfection; Variance analysis; Wound healing; China; New York; United States--US; Shanghai China; miR-505-5p; growth and metastasis; HNF4α; LINC02560; PTC; PDE4C