Hydrogenation of Quinolines Using a Recyclable Phosphine-Free Chiral Cationic Ruthenium Catalyst: Enhancement of Catalyst Stability and Selectivity in an Ionic Liquid

• Published in: Angewandte Chemie (International ed.) Vol. 47; no. 44; pp. 8464 - 8467
• Main Authors: Zhou, Haifeng, Li, Zhiwei, Wang, Zhijian, Wang, Tianli, Xu, Lijin, He, Yanmei, Fan, Qing-Hua, Pan, Jie, Gu, Lianquan, Chan, Albert S.C
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley-VCH Verlag 01.01.2008; WILEY‐VCH Verlag; Wiley
• Subjects: asymmetric catalysis; Catalysis; Chemistry; Chemistry, Multidisciplinary; Hydrogenation; ionic liquids; Ionic Liquids - chemistry; Phosphines - chemistry; Physical Sciences; quinolines; Quinolines - chemistry; Ruthenium - chemistry; Science & Technology; DRAMATIC ENHANCEMENT; MECHANISM; IMINES; COMPLEXES; asymmetric catalysis; hydrogenation; IMMOBILIZATION; KETONES; LIGANDS; ENANTIOSELECTIVE HYDROGENATION; OLEFINS; ionic liquids; ASYMMETRIC HYDROGENATION; quinolines

Liquid assets: The catalyst (S,S)‐1 exhibits an unprecedented reactivity and excellent enantioselectivity for the title reaction when it is carried out in neat ionic liquid (see scheme; BMIM=1‐n‐butyl‐3‐methylimidazolium, Tf=trifluoromethanesulfonyl, Ts=4‐toluenesulfonyl). The ionic liquid facilitat...