Impact of transcranial electrical stimulation on simultaneous stereoelectroencephalography recordings: A randomized sham-controlled study

• Published in: Clinical neurophysiology Vol. 166; pp. 211 - 222
• Main Authors: Simula, Sara, Makhalova, Julia, Pizzo, Francesca, Garnier, Elodie, Damiani, Giada, Mercadal, Borja, Chiara Biagi, Maria, Salvador, Ricardo, Medina-Villalon, Samuel, Ruffini, Giulio, Wendling, Fabrice, George Bénar, Christian, Bartolomei, Fabrice
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2024; Elsevier
• Subjects: Adolescent; Adult; Bioengineering; Brain - physiology; Brain - physiopathology; Electroencephalography - methods; Epilepsies, Partial - physiopathology; Epilepsies, Partial - therapy; Epilepsy; Female; Functional connectivity; Humans; Life Sciences; Male; Middle Aged; Neurology; SEEG; Transcranial Direct Current Stimulation - methods; Transcranial electrical stimulation; Young Adult; Functional connectivity; PSD; EF; tES; Epilepsy; tACS; IED; Transcranial electrical stimulation; AUC; SEEG; tDCS; DRE; FC; epilepsy; Area Under the Curve; Power Spectral Density; transcranial Alternating Current Stimulation; Interictal Epileptiform Discharges; functional connectivity; transcranial Direct Current Stimulation; Drug-Resistant Epilepsy; Electric Field; Stereoelectroencephalography

•This is the first study to examine tES (transcranial electrical stimulation) effects using simultaneous intracranial recordings.•We quantify local and network changes during and closely following application of direct and alternating current stimulation.•Highlighting the variability in tES physiolo...