Inferring gene-to-phenotype and gene-to-disease relationships at Mouse Genome Informatics: challenges and solutions

• Published in: Journal of biomedical semantics Vol. 7; no. 14
• Main Authors: Bello, Susan M, Eppig, Janan T,
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 20.05.2016; BioMed Central
• Subjects: Algorithms; Genes; Genetic aspects; Genomes; Genomics; Mice; Systemic lupus erythematosus

Background Inferring gene-to-phenotype and gene-to-human disease model relationships from annotated mouse phenotypes and disease associations is critical when researching gene function and identifying candidate disease genes. Filtering the various kinds of genotypes to determine which phenotypes are...