Amino acids substitutions in the PB2 protein of H7N9 influenza A viruses are important for virulence in mammalian hosts - Yamayoshi, Seiya; Fukuyama, Satoshi; Yamada, Shinya; Zhao, Dongming; Murakami, Shin; Uraki, Ryuta; Watanabe, Tokiko; Tomita, Yuriko; Neumann, Gabriele; Kawaoka, Yoshihiro (Scientific reports, 2015)
Keywords: 631/326/596; 631/326/596/1578; Adaptation; Amino Acid Substitution; Amino acids; Animals; Asparagine; Aspartic acid; Avian cells; Body Weight; Cell Line; Dogs; Female; Genes, Reporter; Glutamic acid; Growth kinetics; Humanities and Social Sciences; Humans; Infections; Influenza; Influenza A; Influenza A Virus, H7N9 Subtype - metabolism; Influenza A Virus, H7N9 Subtype - pathogenicity; Lung - virology; Lysine; Madin Darby Canine Kidney Cells; Mammals; Mice; Mice, Inbred BALB C; multidisciplinary; Mutation; Nasal Cavity - virology; Pathogenicity; Pathogens; Plasmids; Proteins; Science; Viral Proteins - genetics; Virology; Virulence; Virulence - genetics; Virus Replication; Viruses