The well-coordinated linkage between acidogenicity and aciduricity via insoluble glucans on the surface of Streptococcus mutans

• Published in: Scientific reports Vol. 5; no. 1; p. 18015
• Main Authors: Guo, Lihong, McLean, Jeffrey S., Lux, Renate, He, Xuesong, Shi, Wenyuan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 10.12.2015; Nature Publishing Group
• Subjects: 14/19; 14/34; 14/63; 45/22; 45/29; 45/90; 45/91; 49/39; 631/326/1320; 631/326/421; Adaptation, Biological; Binding sites; Biofilms; Carbohydrates; Dental caries; Dentistry; Enzymes; Gene expression; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Gene regulation; Genetic Linkage; Glucans; Glucans - chemistry; Glucans - metabolism; Glucose; Humanities and Social Sciences; Hydrogen-Ion Concentration; Hypotheses; Microbial Viability; multidisciplinary; pH effects; Protons; Science; Solubility; Streptococcus; Streptococcus infections; Streptococcus mutans - genetics; Streptococcus mutans - metabolism; Sucrose; Sucrose - metabolism; Transcriptome; Virulence; Virulence factors

Streptococcus mutans is considered the principal cariogenic bacterium for dental caries. Despite the recognition of their importance for cariogenesis, the possible coordination among S. mutans’ main virulence factors, including glucan production, acidogenicity and aciduricity, has been less well stu...