Prepulse Inhibition in HIV-Associated Neurocognitive Disorders

• Published in: Journal of the International Neuropsychological Society Vol. 19; no. 6; pp. 709 - 717
• Main Authors: Minassian, Arpi, Henry, Brook L., Woods, Steven Paul, Vaida, Florin, Grant, Igor, Geyer, Mark A., Perry, William
• Format: Journal Article
• Language: English
• Published: New York, USA Cambridge University Press 01.07.2013
• Subjects: Acoustic Stimulation; Acquired immune deficiency syndrome; Adult; AIDS; Cognition Disorders - etiology; Cognition Disorders - psychology; Cognition Disorders - virology; Female; HIV; HIV Infections - complications; Human immunodeficiency virus; Humans; Infections; Inhibition, Psychological; Male; Marijuana; Methamphetamine; Middle Aged; Neuropsychological Tests; Neuropsychology; Psychiatric Status Rating Scales; Reaction Time - physiology; Reflex, Startle - physiology; Statistics, Nonparametric; Toxicology; Urine; Young Adult; Sensorimotor gating; Startle; Impulsivity; Cognition; AIDS dementia complex; Working memory

Sensorimotor inhibition, or the ability to filter out excessive or irrelevant information, theoretically supports a variety of higher-level cognitive functions. Impaired inhibition may be associated with increased impulsive and risky behavior in everyday life. Individuals infected with HIV frequentl...