Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease - Li, Xinzhong; Long, Jintao; He, Taigang; Belshaw, Robert; Scott, James (Scientific reports, 2015)
Keywords: 631/114; 692/617/375/365/1283; Alzheimer Disease - metabolism; Alzheimer's disease; Atrophy; Brain - metabolism; Calcium Signaling; Calcium signalling; Gene expression; Gene Expression Profiling - methods; Gene Expression Regulation; Genomics - methods; Humanities and Social Sciences; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mitochondria; multidisciplinary; Nerve Tissue Proteins - metabolism; Neurodegenerative diseases; NF-κB protein; Nitric oxide; Phosphatidylinositol; Protein interaction; Protein Interaction Mapping - methods; Proteins; Proteome - metabolism; Reactive oxygen species; Science; Signal transduction; Stat3 protein; Systems Integration; TLR4 protein; Toll-like receptors