L-arabinose co-ingestion delays glucose absorption derived from sucrose in healthy men and women: a double-blind, randomised crossover trial

• Published in: British journal of nutrition Vol. 128; no. 6; pp. 1072 - 1081
• Main Authors: Pasmans, Kenneth, Meex, Ruth C.R., Trommelen, Jorn, Senden, Joan M.G., Vaughan, Elaine E., van Loon, Luc J.C., Blaak, Ellen E.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 28.09.2022
• Subjects: Absorption; Adult; Alcoholic beverages; Arabinose; Arabinose - pharmacology; Beverages; Blood Glucose; Body mass index; Carbohydrates; Cross-Over Studies; Diabetes; Digestion; Double-blind studies; Eating; Female; Glucose; Human and Clinical Nutrition; Humans; Hyperglycemia; Ingestion; Insulin; Intravenous administration; Intravenous infusion; intravenous injection; Kinetics; Laboratories; Male; Medical research; Mens health; Plasma; Postprandial Period; Stable isotopes; Sucrose; sucrose alpha-glucosidase; Womens health; Glucose metabolism; Indirect calorimetry; Steady energy; Healthy adults; Sugar-sweetened beverage; Sweetener; Insulin; Sugar
• ISSN: 0007-1145; 1475-2662; 1475-2662
• DOI: 10.1017/S0007114521004153

Dietary interventions to delay carbohydrate digestion or absorption can effectively prevent hyperglycaemia in the early postprandial phase. L-arabinose can specifically inhibit sucrase. It remains to be assessed whether co-ingestion of L-arabinose with sucrose delays sucrose digestion, attenuates su...