Silk fibroin and silk-based biomaterial derivatives for ideal wound dressings

• Published in: International journal of biological macromolecules Vol. 164; pp. 4613 - 4627
• Main Authors: Patil, Priyanka P., Reagan, Michaela R., Bohara, Raghvendra A.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2020
• Subjects: Animals; Bandages; Bandages, Hydrocolloid; biocompatibility; Biocompatible Materials; biodegradability; Biomaterials; Biopolymers; Bombyx mori; Chemical Phenomena; fibroins; Fibroins - chemistry; Fibroins - isolation & purification; Humans; Hydrogels; Manufactured Materials; Materials Testing; Micro-nanoparticles; nanofibers; Nanofibrous matrices; Nanostructures; permeability; Polyvinyl Alcohol; Rats; Rats, Sprague-Dawley; Scaffolds; SF protein; Silk - chemistry; silkworms; Sponges; Surgical Sponges; water vapor; Wound dressing; Wound Healing; Zinc Oxide - administration & dosage; Zinc Oxide - therapeutic use; Hydrogels; Nanofibrous matrices; Films; Micro-nanoparticles; SF protein; Sponges; Wound dressing; Scaffolds; Biomaterials

Silk fibroin (SF) is derived from Bombyx mori silkworm cocoons and has been used in textiles and as a suture material for decades. More recently, SF has been used for various new biomedical applications, including as a wound dressing, owing to its excellent biological and mechanical properties. Spec...