The influence of sex, age and heritability on human skeletal muscle carnosine content

• Published in: Amino acids Vol. 43; no. 1; pp. 13 - 20
• Main Authors: Baguet, Audrey, Everaert, Inge, Achten, Erik, Thomis, Martine, Derave, Wim
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.07.2012; Springer Nature B.V
• Subjects: Adolescent; Adolescents; Adult; adulthood; Adults; Age; Age Factors; Aged; Aged, 80 and over; Analytical Chemistry; Biochemical Engineering; Biochemistry; Biomedical and Life Sciences; boys; Carnosine; Carnosine - analysis; Child; children; Chronology; Correlation; elderly; Female; Females; girls; Heritability; Human; Humans; Life Sciences; Life span; longevity; Magnetic Resonance Spectroscopy; Male; Males; Middle Aged; Muscle, Skeletal - chemistry; Muscle, Skeletal - metabolism; Muscles; Musculoskeletal system; Neurobiology; nuclear magnetic resonance spectroscopy; Older people; Original Article; Polycarbonates; Population studies; Proteomics; Proton magnetic resonance; Puberty; Sex; Sex Factors; Skeletal muscle; Soleus muscle; twins; Twins - genetics; Young Adult; Young adults; Aging; Puberty; Heritability; H-MRS; Muscle carnosine

The dipeptide carnosine is found in high concentrations in human skeletal muscle and shows large inter-individual differences. Sex and age are determining factors, however, systematic studies investigating the sex effects on muscle carnosine content throughout the human lifespan are lacking. Despite...