Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 128; no. 3; p. 541
• Main Authors: O'Mahony, Liam, McCarthy, Jane, Kelly, Peter, Hurley, George, Luo, Fangyi, Chen, Kersang, O'Sullivan, Gerald C, Kiely, Barry, Collins, J Kevin, Shanahan, Fergus, Quigley, Eamonn M M
• Format: Journal Article
• Language: English
• Published: United States 01.03.2005
• Subjects: Adult; Aged; Bifidobacterium - isolation & purification; Cytokines - blood; Feces - microbiology; Female; Humans; Irritable Bowel Syndrome - blood; Irritable Bowel Syndrome - physiopathology; Irritable Bowel Syndrome - therapy; Lactobacillus - isolation & purification; Male; Middle Aged; Monocytes - metabolism; Probiotics - adverse effects; Probiotics - isolation & purification; Probiotics - therapeutic use; Quality of Life; Treatment Outcome

The aim of this study was to compare the response of symptoms and cytokine ratios in irritable bowel syndrome (IBS) with ingestion of probiotic preparations containing a lactobacillus or bifidobacterium strain. Seventy-seven subjects with IBS were randomized to receive either Lactobacillus salivariu...