Varicella Zoster Virus DNA at Inoculation Sites and in Saliva After Zostavax Immunization
Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 10 6⁶) and in saliva colle...
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| Published in | The Journal of infectious diseases Vol. 203; no. 11; pp. 1542 - 1545 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
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Oxford
Oxford University Press
01.06.2011
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| Series | Editor's Choice |
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| Abstract | Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 10 6⁶) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks. |
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| AbstractList | Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 10(6)) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks.Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 10(6)) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks. Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 10 6⁶) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks. Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 10 6 ) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks. Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 X 10 super(6)) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks. Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 106) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks. Analysis of 36 individuals over age 60 years who were immunized with Zostavax revealed varicella zoster virus (VZV) DNA in swabs of skin inoculation sites obtained immediately after immunization in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 × 10(6)) and in saliva collected over 28 days in 21 (58%) of 36 subjects (copy number, 20 to 248). Genotypic analysis of DNA extracted from 9 random saliva samples identified vaccine virus in all instances. In some immunized individuals over age 60, vaccine virus DNA is shed in saliva up to 4 weeks. |
| Author | Pierson, Duane L. Mehta, Satish K. Nagel, Maria A. Gilden, Don Cohrs, Randall J. Tyring, Stephen K. Schmid, D. Scott |
| AuthorAffiliation | 5 Microbiology, University of Colorado School of Medicine, Aurora 1 Space Life Sciences, NASA, Lyndon B. Johnson Space Center 3 University of Texas Health Science Center, Houston, Texas 4 Department of Neurology 6 National VZV Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia 2 Enterprise Advisory Services, Inc |
| AuthorAffiliation_xml | – name: 2 Enterprise Advisory Services, Inc – name: 4 Department of Neurology – name: 5 Microbiology, University of Colorado School of Medicine, Aurora – name: 1 Space Life Sciences, NASA, Lyndon B. Johnson Space Center – name: 3 University of Texas Health Science Center, Houston, Texas – name: 6 National VZV Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia |
| Author_xml | – sequence: 1 givenname: Duane L. surname: Pierson fullname: Pierson, Duane L. – sequence: 2 givenname: Satish K. surname: Mehta fullname: Mehta, Satish K. – sequence: 3 givenname: Don surname: Gilden fullname: Gilden, Don – sequence: 4 givenname: Randall J. surname: Cohrs fullname: Cohrs, Randall J. – sequence: 5 givenname: Maria A. surname: Nagel fullname: Nagel, Maria A. – sequence: 6 givenname: D. Scott surname: Schmid fullname: Schmid, D. Scott – sequence: 7 givenname: Stephen K. surname: Tyring fullname: Tyring, Stephen K. |
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| Cites_doi | 10.1086/522161 10.1002/jmv.21173 10.1002/jmv.10555 10.1086/508539 10.1056/NEJMoa051016 10.1093/infdis/160.3.535 10.1086/527420 10.1086/510532 10.1016/0166-0934(82)90073-8 10.1086/527419 10.1086/599381 10.1128/JCM.38.12.4315-4319.2000 |
| ContentType | Journal Article |
| Copyright | Copyright © 2011 Oxford University Press on behalf of the Infectious Diseases Society of America The Author 2011. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com 2011 2015 INIST-CNRS |
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| Keywords | Virus Infection Varicella zoster virus Immunization Herpesviridae Alphaherpesvirinae Vaccine Saliva |
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| References | Satyaprakash ( key 20170702142720_bib1) 2009; 200 Gilden ( key 20170702142720_bib8) 1982; 4 Arvin ( key 20170702142720_bib2) 2010; 342 Chaves ( key 20170702142720_bib12) 2008; 197 Gilden ( key 20170702142720_bib3) 2010; 342 Hammerschlag ( key 20170702142720_bib14) 1989; 160 Oxman ( key 20170702142720_bib4) 2005; 352 Mehta ( key 20170702142720_bib5) 2008; 197 Loparev ( key 20170702142720_bib9) 2000; 38 Cohrs ( key 20170702142720_bib6) 2008; 80 Mehta ( key 20170702142720_bib7) 2004; 72 Taha ( key 20170702142720_bib15) 2006; 43 Harpaz ( key 20170702142720_bib13) 2008; 57 Loparev ( key 20170702142720_bib10) 2007; 195 Lopez ( key 20170702142720_bib11) 2008; 197 17051496 - Clin Infect Dis. 2006 Nov 15;43(10):1301-3 19469706 - J Infect Dis. 2009 Jul 1;200(1):26-32 18260763 - J Infect Dis. 2008 Mar 1;197(5):654-7 20186614 - Curr Top Microbiol Immunol. 2010;342:243-53 20397071 - Curr Top Microbiol Immunol. 2010;342:189-209 2547882 - J Infect Dis. 1989 Sep;160(3):535-7 15930418 - N Engl J Med. 2005 Jun 2;352(22):2271-84 18260757 - J Infect Dis. 2008 Mar 1;197(5):646-53 18528318 - MMWR Recomm Rep. 2008 Jun 6;57(RR-5):1-30; quiz CE2-4 11101557 - J Clin Microbiol. 2000 Dec;38(12):4315-9 14635028 - J Med Virol. 2004 Jan;72(1):174-9 18419393 - J Infect Dis. 2008 Mar 1;197 Suppl 2:S170-7 18428120 - J Med Virol. 2008 Jun;80(6):1116-22 17230409 - J Infect Dis. 2007 Feb 15;195(4):502-10 6286707 - J Virol Methods. 1982 May;4(4-5):263-75 |
| References_xml | – volume: 197 start-page: S170 year: 2008 ident: key 20170702142720_bib12 article-title: Safety of varicella vaccine after licensure in the United States: experience from reports to the vaccine adverse event reporting system, 1995–2005 publication-title: J Infect Dis doi: 10.1086/522161 – volume: 80 start-page: 1116 year: 2008 ident: key 20170702142720_bib6 article-title: Asymptomatic reactivation and shed of infectious varicella zoster virus in astronauts publication-title: J Med Virol doi: 10.1002/jmv.21173 – volume: 72 start-page: 174 year: 2004 ident: key 20170702142720_bib7 article-title: Stress-induced subclinical reactivation of varicella zoster virus in astronauts publication-title: J Med Virol doi: 10.1002/jmv.10555 – volume: 43 start-page: 1301 year: 2006 ident: key 20170702142720_bib15 article-title: Reactivation of 2 genetically distinct varicella-zoster viruses in the same individual publication-title: Clin Infect Dis doi: 10.1086/508539 – volume: 342 start-page: 243 year: 2010 ident: key 20170702142720_bib3 article-title: Neurological disease produced by varicella zoster virus reactivation without rash publication-title: Curr Top Microbiol Immunol – volume: 352 start-page: 2271 year: 2005 ident: key 20170702142720_bib4 article-title: A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults publication-title: N Engl J Med doi: 10.1056/NEJMoa051016 – volume: 160 start-page: 535 year: 1989 ident: key 20170702142720_bib14 article-title: Herpes zoster in an adult recipient of live attenuated varicella vaccine publication-title: J Infect Dis doi: 10.1093/infdis/160.3.535 – volume: 57 start-page: 1 year: 2008 ident: key 20170702142720_bib13 article-title: Prevention of herpes zoster: recommendations of the Advisory Committee on immunization Practices (ACIP) publication-title: MMWR Recomm Rep – volume: 342 start-page: 189 year: 2010 ident: key 20170702142720_bib2 article-title: Varicella-zoster virus T cell tropism and the pathogenesis of skin infection publication-title: Curr Top Microbiol Immunol – volume: 197 start-page: 654 year: 2008 ident: key 20170702142720_bib5 article-title: Varicella-zoster virus in the saliva of patients with herpes zoster publication-title: J Infect Dis doi: 10.1086/527420 – volume: 195 start-page: 502 year: 2007 ident: key 20170702142720_bib10 article-title: DNA sequence variability in isolates recovered from patients with post vaccination rash or herpes zoster caused by Oka varicella vaccine publication-title: J Infect Dis doi: 10.1086/510532 – volume: 4 start-page: 263 year: 1982 ident: key 20170702142720_bib8 article-title: Extraction of cell-associated varicella-zoster virus DNA with triton X-100-NaCl publication-title: J Virol Methods doi: 10.1016/0166-0934(82)90073-8 – volume: 197 start-page: 646 year: 2008 ident: key 20170702142720_bib11 article-title: Transmission of a newly characterized strain of varicella-zoster virus from a patient with herpes zoster in a long-term-care facility, West Virginia, 2004 publication-title: J Infect Dis doi: 10.1086/527419 – volume: 200 start-page: 26 year: 2009 ident: key 20170702142720_bib1 article-title: Viremia in acute herpes zoster publication-title: J Infect Dis doi: 10.1086/599381 – volume: 38 start-page: 4315 year: 2000 ident: key 20170702142720_bib9 article-title: Rapid genotyping of varicella-zoster virus vaccine and wild-type strains with fluorophore-labeled hybridization probes publication-title: J Clin Microbiol doi: 10.1128/JCM.38.12.4315-4319.2000 – reference: 19469706 - J Infect Dis. 2009 Jul 1;200(1):26-32 – reference: 17230409 - J Infect Dis. 2007 Feb 15;195(4):502-10 – reference: 6286707 - J Virol Methods. 1982 May;4(4-5):263-75 – reference: 14635028 - J Med Virol. 2004 Jan;72(1):174-9 – reference: 20186614 - Curr Top Microbiol Immunol. 2010;342:243-53 – reference: 11101557 - J Clin Microbiol. 2000 Dec;38(12):4315-9 – reference: 18260763 - J Infect Dis. 2008 Mar 1;197(5):654-7 – reference: 18419393 - J Infect Dis. 2008 Mar 1;197 Suppl 2:S170-7 – reference: 20397071 - Curr Top Microbiol Immunol. 2010;342:189-209 – reference: 2547882 - J Infect Dis. 1989 Sep;160(3):535-7 – reference: 18428120 - J Med Virol. 2008 Jun;80(6):1116-22 – reference: 17051496 - Clin Infect Dis. 2006 Nov 15;43(10):1301-3 – reference: 18260757 - J Infect Dis. 2008 Mar 1;197(5):646-53 – reference: 15930418 - N Engl J Med. 2005 Jun 2;352(22):2271-84 – reference: 18528318 - MMWR Recomm Rep. 2008 Jun 6;57(RR-5):1-30; quiz CE2-4 |
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| SubjectTerms | Aged Aged, 80 and over Applied microbiology Biological and medical sciences Chickenpox DNA DNA, Viral - analysis DNA, Viral - isolation & purification Female Fundamental and applied biological sciences. Psychology Herpes zoster Herpes zoster vaccine Herpes Zoster Vaccine - administration & dosage Herpesvirus 3, Human - genetics Herpesvirus 3, Human - immunology Herpesvirus 3, Human - isolation & purification Humans Immunization Infectious diseases Inoculation Major and Brief Reports Male Medical sciences Microbiology Middle Aged Miscellaneous Saliva Saliva - virology Skin - virology Vaccination Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Varicella zoster encephalitis Varicella-zoster virus Virology Viruses |
| Title | Varicella Zoster Virus DNA at Inoculation Sites and in Saliva After Zostavax Immunization |
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