An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1-infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study) - Fitzgerald, D. W.; Janes, H.; Robertson, M.; Coombs, R.; Frank, I.; Gilbert, P.; Loufty, M.; Mehrotra, D.; Duerr, A. (The Journal of infectious diseases, 2011)
Keywords: Adenovirus; Adenoviruses, Human - genetics; Adenoviruses, Human - immunology; Adult; AIDS; AIDS Vaccines - immunology; Anti-Retroviral Agents - therapeutic use; Applied microbiology; Biological and medical sciences; Blotting, Western; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes - immunology; Circumcision, Male; Disease-Free Survival; Double-Blind Method; Fundamental and applied biological sciences. Psychology; Genetic Vectors; HIV; HIV 1; HIV Infections - drug therapy; HIV Infections - immunology; HIV Infections - prevention & control; HIV-1 - genetics; HIV-1 - immunology; HIV-1 - physiology; HIV/AIDS; HLA antigens; Human immunodeficiency virus 1; Human viral diseases; Humans; Immunity, Cellular; Infections; Infectious diseases; Major and Brief Reports; Male; Medical sciences; Microbiology; Middle Aged; Miscellaneous; Placebos; Proportional Hazards Models; RNA; RNA, Viral - blood; RNA, Viral - immunology; T lymphocytes; Vaccination; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Viral load; Viral Load - drug effects; Virology; Young Adult; Disease development; Immunopathology; HIV-1 virus; Retroviridae; AIDS; Cellular immunity; Vaccine; Immune deficiency; Lentivirus; Virus; Infection; Viral disease; Human immunodeficiency virus; Vector