Cigarette Smoking, Genetic Variants in Carcinogen-metabolizing Enzymes, and Colorectal Cancer Risk - Cleary, Sean P.; Cotterchio, Michelle; Shi, Ellen; Gallinger, Steven; Harper, Patricia (American journal of epidemiology, 2010)
Keywords: Adult; Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases - genetics; Arylamine N-Acetyltransferase - genetics; Arylsulfotransferase - genetics; Biological and medical sciences; Biomarkers - blood; Carcinogens; Case-Control Studies; Cigarettes; Colon; Colorectal cancer; Colorectal carcinoma; colorectal neoplasms; Colorectal Neoplasms - enzymology; Colorectal Neoplasms - epidemiology; Colorectal Neoplasms - etiology; Colorectal Neoplasms - genetics; Confidence Intervals; Cytochrome P-450 CYP1A1 - genetics; Cytochrome P-450 CYP1A2 - genetics; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2E1 - genetics; enzymes; Epidemiology; Epoxide Hydrolases - genetics; Female; Gastroenterology. Liver. Pancreas. Abdomen; General aspects; genes; Genetic diversity; Genetic variance; genetic variation; Genetics; Genotype; Genotypes; Glutathione Transferase - genetics; Health risks; Humans; Isoenzymes - genetics; Male; Medical Records; Medical sciences; Middle Aged; Miscellaneous; Multivariate Analysis; neoplasm; Odds Ratio; Ontario - epidemiology; Original Contributions; Polymorphism, Genetic; Public health. Hygiene; Public health. Hygiene-occupational medicine; Retrospective Studies; Risk; Risk reduction; Smoking; Smoking - adverse effects; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Surveys and Questionnaires; Tobacco, tobacco smoking; Toxicology; Tumors; Ontario; Canada, Ontario; Rectal disease; Colorectal cancer; Tobacco smoking; Risk; enzymes; Epidemiology; Gene; colorectal neoplasms; smoking; Intestinal disease; Genetics; carcinogens; Public health; Enzyme; genes; Genetic variant; genetic variation; Malignant tumor; Colonic disease; Carcinogen; Tobacco; Risk factor; Digestive diseases; neoplasm; Cancer; Polymorphism