Oxidative Stress and the Pathogenesis of Alzheimer's Disease

• Published in: Oxidative medicine and cellular longevity Vol. 2013; no. 2013; pp. 1 - 10
• Main Authors: Zhao, Yan, Zhao, Baolu
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Puplishing Corporation 01.01.2013; Hindawi Publishing Corporation
• Subjects: Alzheimer Disease - metabolism; Humans; Oxidative Stress - physiology; Reactive Oxygen Species - metabolism; Review

Alzheimer's disease (AD) is the most common neurodegenerative disease that causes dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other cognitive functions, which eventually leads to a complete incapacity and death. A complicated array of molecular events...