Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist - Rizzo, Giovanni; Passeri, Daniela; De Franco, Francesca; Ciaccioli, Gianmario; Donadio, Loredana; Rizzo, Giorgia; Orlandi, Stefano; Sadeghpour, Bahman; Wang, Xiaoxin X.; Jiang, Tao; Levi, Moshe; Pruzanski, Mark; et al. (Molecular pharmacology, 2010)
Keywords: Animals; Bile Acids and Salts - chemical synthesis; Bile Acids and Salts - metabolism; Bile Acids and Salts - pharmacology; CHO Cells; Cricetinae; Cricetulus; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Obese; NIH 3T3 Cells; Receptors, Cytoplasmic and Nuclear - agonists; Receptors, Cytoplasmic and Nuclear - physiology; Receptors, G-Protein-Coupled - agonists; Receptors, G-Protein-Coupled - physiology; FXR; SR-BI; mP; DMSO; GE1929; NT; INT-747; ORO; WD; INT-767; DMEM; LDH; HDL; PPAR; CYP450; LDL; STZ; GW7647; WT; CDCA; hERG; GLP-1; FXRE; MS; h; siRNA; LCA; INT-777; D2; HEK; E-4031; CAR; T0901317; CRE; FCS; GPCR; PCR; BrdU; TR-FRET; BA; SR-12813