Who Is Who in Adenosine Transport

• Published in: Frontiers in pharmacology Vol. 9; p. 627
• Main Authors: Pastor Anglada, Marçal, Pérez Torras, Sandra
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media 14.06.2018; Frontiers Media S.A
• Subjects: Adenosina; Adenosine; CNT; ENT; Pharmacology; purinergic signaling; transporters; adenosine; CNT; purinergic signaling; ENT; transporters

Extracellular adenosine concentrations are regulated by a panel of membrane transporters which, in most cases, mediate its uptake into cells. Adenosine transporters belong to two gene families encoding Equilibrative and Concentrative Nucleoside Transporter proteins (ENTs and CNTs, respectively). The...