Glutathione: subcellular distribution and membrane transport

• Published in: Biochemistry and cell biology Vol. 97; no. 3; pp. 270 - 289
• Main Authors: Oestreicher, Julian, Morgan, Bruce
• Format: Journal Article
• Language: English
• Published: Ottawa NRC Research Press 01.05.2019; Canadian Science Publishing NRC Research Press
• Subjects: Biological transport; Cell membranes; Compartments; Cytosol; Eukaryotes; Fungi; Glutathione; Homeostasis; Physiological aspects; Physiological research; Plastids; Replenishment; Thiols; Transport

Glutathione (γ-l-glutamyl-l-cysteinylglycine) is a small tripeptide found at millimolar concentrations in nearly all eukaryotes as well as many prokaryotic cells. Glutathione synthesis is restricted to the cytosol in animals and fungi and to the cytosol and plastids in plants. Nonetheless, glutathio...