Porcine epidemic diarrhea virus (PEDV): An update on etiology, transmission, pathogenesis, and prevention and control

• Published in: Virus research Vol. 286; p. 198045
• Main Authors: Jung, Kwonil, Saif, Linda J., Wang, Qiuhong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2020
• Subjects: Aerosols; airborne transmission; Animals; B-lymphocytes; biosecurity; Coronavirus; Coronavirus Infections - pathology; Coronavirus Infections - prevention & control; Coronavirus Infections - transmission; diarrhea; disease outbreaks; Disease Progression; enteritis; etiology; farms; herd immunity; ileum; Immunity, Humoral - immunology; immunoglobulin A; innate immunity; Intestinal Mucosa - pathology; Intestinal Mucosa - virology; jejunum; mortality; nasal cavity; Pathogenesis; PEDV; piglets; Pigs; Porcine epidemic diarrhea virus; Porcine epidemic diarrhea virus - genetics; Porcine epidemic diarrhea virus - immunology; Porcine epidemic diarrhea virus - pathogenicity; Prevention; Receptors, Virus - metabolism; RNA; sows; Swine; swine diseases; Swine Diseases - pathology; Swine Diseases - transmission; Swine Diseases - virology; United States; vaccines; viral shedding; Viral Tropism - physiology; viremia; Viremia - blood; virulence; viruses; vomiting; United States; Prevention; Pigs; Porcine epidemic diarrhea virus; PEDV; Coronavirus; Pathogenesis

•Porcine epidemic diarrhea virus (PEDV) causes acute diarrhea, dehydration and high mortality in neonatal pig.•S INDEL and non-S INDEL strains were detected during the diarrheal disease outbreak in US swine in 2013–2014.•The non-S INDEL PEDV was highly virulent, whereas the S INDEL PEDV caused milde...