The complete chloroplast genomes of Tetrastigma hemsleyanum (Vitaceae) from different regions of China: molecular structure, comparative analysis and development of DNA barcodes for its geographical origin discrimination

Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on th...

Full description

Saved in:
Bibliographic Details
Published inBMC genomics Vol. 23; no. 1; pp. 1 - 31
Main Authors Dong, Shujie, Zhou, Manjia, Zhu, Jinxing, Wang, Qirui, Ge, Yuqing, Cheng, Rubin
Format Journal Article
LanguageEnglish
Published London BioMed Central Ltd 26.08.2022
BioMed Central
BMC
Subjects
Anticancer properties
Apoptosis
Bar codes
Biomarkers
Chloroplast genome
Chloroplasts
Comparative analysis
Deoxyribonucleic acid
Discrimination
Distribution
DNA
DNA barcoding
DNA barcoing markers
Flavonoids
Gene order
Gene sequencing
Genes
Genetic aspects
Genomes
Genomics
Geographical distribution
Geographical origins
Germplasm
Herbal medicine
Inflammation
Medicinal plants
Methods
Molecular structure
Morphology
Nucleotide diversity
Origins
Phylogenetic relationships
Phylogenetics
Phylogeny
Proteins
rRNA
Taxonomy
Tetrastigma hemsleyanum
tRNA
Tumors
Vitaceae
China
Online AccessGet full text

Cover

Abstract Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on the quality of T. hemsleyanum root from different regions, requiring the discrimination strategy for the geographical origins. This study characterized five complete chloroplast (cp) genomes of T. hemsleynum samples from different regions, and conducted a comparative analysis with other representing species from family Vitaceae to reveal the structural variations, informative markers and phylogenetic relationships. The sequenced cp genomes of T. hemsleyanum exhibited a conserved quadripartite structure with full length ranging from 160,124 bp of Jiangxi Province to 160,618 bp of Zhejiang Province. We identified 112 unique genes (80 protein-coding, 28 tRNA and 4 rRNA genes) in the cp genomes of T. hemsleyanum with highly similar gene order, content and structure. The IR contraction/expansion events occurred on the junctions of ycf1, rps19 and rpl2 genes with different degrees, causing the differences of genome sizes in T. hemsleyanum and Vitaceae plants. The number of SSR markers discovered in T. hemsleyanum was 56-57, exhibiting multiple differences among the five geographic groups. Phylogenetic analysis based on conserved cp genome proteins strongly grouped the five T. hemsleyanum species into one clade, showing a sister relationship with T. planicaule. Comparative analysis of the cp genomes from T. hemsleyanum and Vitaceae revealed five highly variable spacers, including 4 intergenic regions and one protein-coding gene (ycf1). Furthermore, five mutational hotspots were observed among T. hemsleyanum cp genomes from different regions, providing data for designing DNA barcodes trnL and trnN. The combination of molecular markers of trnL and trnN clustered the T. hemsleyanum samples from different regions into four groups, thus successfully separating specimens of Sichuan and Zhejiang from other areas. Our study obtained the chloroplast genomes of T. hemsleyanum from different regions, and provided a potential molecular tracing tool for determining the geographical origins of T. hemsleyanum, as well as important insights into the molecular identification approach and and phylogeny in Tetrastigma genus and Vitaceae family.
AbstractList Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on the quality of T. hemsleyanum root from different regions, requiring the discrimination strategy for the geographical origins. This study characterized five complete chloroplast (cp) genomes of T. hemsleynum samples from different regions, and conducted a comparative analysis with other representing species from family Vitaceae to reveal the structural variations, informative markers and phylogenetic relationships. The sequenced cp genomes of T. hemsleyanum exhibited a conserved quadripartite structure with full length ranging from 160,124 bp of Jiangxi Province to 160,618 bp of Zhejiang Province. We identified 112 unique genes (80 protein-coding, 28 tRNA and 4 rRNA genes) in the cp genomes of T. hemsleyanum with highly similar gene order, content and structure. The IR contraction/expansion events occurred on the junctions of ycf1, rps19 and rpl2 genes with different degrees, causing the differences of genome sizes in T. hemsleyanum and Vitaceae plants. The number of SSR markers discovered in T. hemsleyanum was 56-57, exhibiting multiple differences among the five geographic groups. Phylogenetic analysis based on conserved cp genome proteins strongly grouped the five T. hemsleyanum species into one clade, showing a sister relationship with T. planicaule. Comparative analysis of the cp genomes from T. hemsleyanum and Vitaceae revealed five highly variable spacers, including 4 intergenic regions and one protein-coding gene (ycf1). Furthermore, five mutational hotspots were observed among T. hemsleyanum cp genomes from different regions, providing data for designing DNA barcodes trnL and trnN. The combination of molecular markers of trnL and trnN clustered the T. hemsleyanum samples from different regions into four groups, thus successfully separating specimens of Sichuan and Zhejiang from other areas. Our study obtained the chloroplast genomes of T. hemsleyanum from different regions, and provided a potential molecular tracing tool for determining the geographical origins of T. hemsleyanum, as well as important insights into the molecular identification approach and and phylogeny in Tetrastigma genus and Vitaceae family.
Background Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on the quality of T. hemsleyanum root from different regions, requiring the discrimination strategy for the geographical origins. Result This study characterized five complete chloroplast (cp) genomes of T. hemsleynum samples from different regions, and conducted a comparative analysis with other representing species from family Vitaceae to reveal the structural variations, informative markers and phylogenetic relationships. The sequenced cp genomes of T. hemsleyanum exhibited a conserved quadripartite structure with full length ranging from 160,124 bp of Jiangxi Province to 160,618 bp of Zhejiang Province. We identified 112 unique genes (80 protein-coding, 28 tRNA and 4 rRNA genes) in the cp genomes of T. hemsleyanum with highly similar gene order, content and structure. The IR contraction/expansion events occurred on the junctions of ycf1, rps19 and rpl2 genes with different degrees, causing the differences of genome sizes in T. hemsleyanum and Vitaceae plants. The number of SSR markers discovered in T. hemsleyanum was 56–57, exhibiting multiple differences among the five geographic groups. Phylogenetic analysis based on conserved cp genome proteins strongly grouped the five T. hemsleyanum species into one clade, showing a sister relationship with T. planicaule. Comparative analysis of the cp genomes from T. hemsleyanum and Vitaceae revealed five highly variable spacers, including 4 intergenic regions and one protein-coding gene (ycf1). Furthermore, five mutational hotspots were observed among T. hemsleyanum cp genomes from different regions, providing data for designing DNA barcodes trnL and trnN. The combination of molecular markers of trnL and trnN clustered the T. hemsleyanum samples from different regions into four groups, thus successfully separating specimens of Sichuan and Zhejiang from other areas. Conclusion Our study obtained the chloroplast genomes of T. hemsleyanum from different regions, and provided a potential molecular tracing tool for determining the geographical origins of T. hemsleyanum, as well as important insights into the molecular identification approach and and phylogeny in Tetrastigma genus and Vitaceae family.
Abstract Background Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on the quality of T. hemsleyanum root from different regions, requiring the discrimination strategy for the geographical origins. Result This study characterized five complete chloroplast (cp) genomes of T. hemsleynum samples from different regions, and conducted a comparative analysis with other representing species from family Vitaceae to reveal the structural variations, informative markers and phylogenetic relationships. The sequenced cp genomes of T. hemsleyanum exhibited a conserved quadripartite structure with full length ranging from 160,124 bp of Jiangxi Province to 160,618 bp of Zhejiang Province. We identified 112 unique genes (80 protein-coding, 28 tRNA and 4 rRNA genes) in the cp genomes of T. hemsleyanum with highly similar gene order, content and structure. The IR contraction/expansion events occurred on the junctions of ycf1, rps19 and rpl2 genes with different degrees, causing the differences of genome sizes in T. hemsleyanum and Vitaceae plants. The number of SSR markers discovered in T. hemsleyanum was 56–57, exhibiting multiple differences among the five geographic groups. Phylogenetic analysis based on conserved cp genome proteins strongly grouped the five T. hemsleyanum species into one clade, showing a sister relationship with T. planicaule. Comparative analysis of the cp genomes from T. hemsleyanum and Vitaceae revealed five highly variable spacers, including 4 intergenic regions and one protein-coding gene (ycf1). Furthermore, five mutational hotspots were observed among T. hemsleyanum cp genomes from different regions, providing data for designing DNA barcodes trnL and trnN. The combination of molecular markers of trnL and trnN clustered the T. hemsleyanum samples from different regions into four groups, thus successfully separating specimens of Sichuan and Zhejiang from other areas. Conclusion Our study obtained the chloroplast genomes of T. hemsleyanum from different regions, and provided a potential molecular tracing tool for determining the geographical origins of T. hemsleyanum, as well as important insights into the molecular identification approach and and phylogeny in Tetrastigma genus and Vitaceae family.
Background Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on the quality of T. hemsleyanum root from different regions, requiring the discrimination strategy for the geographical origins. Result This study characterized five complete chloroplast (cp) genomes of T. hemsleynum samples from different regions, and conducted a comparative analysis with other representing species from family Vitaceae to reveal the structural variations, informative markers and phylogenetic relationships. The sequenced cp genomes of T. hemsleyanum exhibited a conserved quadripartite structure with full length ranging from 160,124 bp of Jiangxi Province to 160,618 bp of Zhejiang Province. We identified 112 unique genes (80 protein-coding, 28 tRNA and 4 rRNA genes) in the cp genomes of T. hemsleyanum with highly similar gene order, content and structure. The IR contraction/expansion events occurred on the junctions of ycf1, rps19 and rpl2 genes with different degrees, causing the differences of genome sizes in T. hemsleyanum and Vitaceae plants. The number of SSR markers discovered in T. hemsleyanum was 56-57, exhibiting multiple differences among the five geographic groups. Phylogenetic analysis based on conserved cp genome proteins strongly grouped the five T. hemsleyanum species into one clade, showing a sister relationship with T. planicaule. Comparative analysis of the cp genomes from T. hemsleyanum and Vitaceae revealed five highly variable spacers, including 4 intergenic regions and one protein-coding gene (ycf1). Furthermore, five mutational hotspots were observed among T. hemsleyanum cp genomes from different regions, providing data for designing DNA barcodes trnL and trnN. The combination of molecular markers of trnL and trnN clustered the T. hemsleyanum samples from different regions into four groups, thus successfully separating specimens of Sichuan and Zhejiang from other areas. Conclusion Our study obtained the chloroplast genomes of T. hemsleyanum from different regions, and provided a potential molecular tracing tool for determining the geographical origins of T. hemsleyanum, as well as important insights into the molecular identification approach and and phylogeny in Tetrastigma genus and Vitaceae family. Keywords: Tetrastigma hemsleyanum, Chloroplast genome, Phylogenetic relationships, Nucleotide diversity, DNA barcoing markers, Geographical origins
Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on the quality of T. hemsleyanum root from different regions, requiring the discrimination strategy for the geographical origins.BACKGROUNDTetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-inflammatory activities. However, obvious differences were observed on the quality of T. hemsleyanum root from different regions, requiring the discrimination strategy for the geographical origins.This study characterized five complete chloroplast (cp) genomes of T. hemsleynum samples from different regions, and conducted a comparative analysis with other representing species from family Vitaceae to reveal the structural variations, informative markers and phylogenetic relationships. The sequenced cp genomes of T. hemsleyanum exhibited a conserved quadripartite structure with full length ranging from 160,124 bp of Jiangxi Province to 160,618 bp of Zhejiang Province. We identified 112 unique genes (80 protein-coding, 28 tRNA and 4 rRNA genes) in the cp genomes of T. hemsleyanum with highly similar gene order, content and structure. The IR contraction/expansion events occurred on the junctions of ycf1, rps19 and rpl2 genes with different degrees, causing the differences of genome sizes in T. hemsleyanum and Vitaceae plants. The number of SSR markers discovered in T. hemsleyanum was 56-57, exhibiting multiple differences among the five geographic groups. Phylogenetic analysis based on conserved cp genome proteins strongly grouped the five T. hemsleyanum species into one clade, showing a sister relationship with T. planicaule. Comparative analysis of the cp genomes from T. hemsleyanum and Vitaceae revealed five highly variable spacers, including 4 intergenic regions and one protein-coding gene (ycf1). Furthermore, five mutational hotspots were observed among T. hemsleyanum cp genomes from different regions, providing data for designing DNA barcodes trnL and trnN. The combination of molecular markers of trnL and trnN clustered the T. hemsleyanum samples from different regions into four groups, thus successfully separating specimens of Sichuan and Zhejiang from other areas.RESULTThis study characterized five complete chloroplast (cp) genomes of T. hemsleynum samples from different regions, and conducted a comparative analysis with other representing species from family Vitaceae to reveal the structural variations, informative markers and phylogenetic relationships. The sequenced cp genomes of T. hemsleyanum exhibited a conserved quadripartite structure with full length ranging from 160,124 bp of Jiangxi Province to 160,618 bp of Zhejiang Province. We identified 112 unique genes (80 protein-coding, 28 tRNA and 4 rRNA genes) in the cp genomes of T. hemsleyanum with highly similar gene order, content and structure. The IR contraction/expansion events occurred on the junctions of ycf1, rps19 and rpl2 genes with different degrees, causing the differences of genome sizes in T. hemsleyanum and Vitaceae plants. The number of SSR markers discovered in T. hemsleyanum was 56-57, exhibiting multiple differences among the five geographic groups. Phylogenetic analysis based on conserved cp genome proteins strongly grouped the five T. hemsleyanum species into one clade, showing a sister relationship with T. planicaule. Comparative analysis of the cp genomes from T. hemsleyanum and Vitaceae revealed five highly variable spacers, including 4 intergenic regions and one protein-coding gene (ycf1). Furthermore, five mutational hotspots were observed among T. hemsleyanum cp genomes from different regions, providing data for designing DNA barcodes trnL and trnN. The combination of molecular markers of trnL and trnN clustered the T. hemsleyanum samples from different regions into four groups, thus successfully separating specimens of Sichuan and Zhejiang from other areas.Our study obtained the chloroplast genomes of T. hemsleyanum from different regions, and provided a potential molecular tracing tool for determining the geographical origins of T. hemsleyanum, as well as important insights into the molecular identification approach and and phylogeny in Tetrastigma genus and Vitaceae family.CONCLUSIONOur study obtained the chloroplast genomes of T. hemsleyanum from different regions, and provided a potential molecular tracing tool for determining the geographical origins of T. hemsleyanum, as well as important insights into the molecular identification approach and and phylogeny in Tetrastigma genus and Vitaceae family.
ArticleNumber 620
Audience Academic
Author Dong, Shujie
Zhu, Jinxing
Ge, Yuqing
Zhou, Manjia
Wang, Qirui
Cheng, Rubin
Author_xml – sequence: 1
  givenname: Shujie
  surname: Dong
  fullname: Dong, Shujie
– sequence: 2
  givenname: Manjia
  surname: Zhou
  fullname: Zhou, Manjia
– sequence: 3
  givenname: Jinxing
  surname: Zhu
  fullname: Zhu, Jinxing
– sequence: 4
  givenname: Qirui
  surname: Wang
  fullname: Wang, Qirui
– sequence: 5
  givenname: Yuqing
  surname: Ge
  fullname: Ge, Yuqing
– sequence: 6
  givenname: Rubin
  surname: Cheng
  fullname: Cheng, Rubin
BookMark eNp9U0tv1DAQjlARfcAf4GSJSyuRYnsTx-GAVJVXpQokKFwtxxlnXTnx1nYq-l_5MczuVsBWCPmQ0eR7jMczh8XeFCYoiueMnjImxavEuBRVSTkvqWzqumweFQesaljJmaj2_or3i8OUrilljeT1k2J_ISiXksqD4ufVEogJ48pDxmDpQwwrr1MmA0xhhESCJVeQI6bcMGqyhDF5uNPTPJLj7y5rAxpOiI1hJL2zFiJMmUQYXJg25POlm_RrMgYPZvY6kpTjbPIc4eXGWEed3S0QPWl_l1zCoCc93IIPq3GthRpvP52RTkcTeizIhkhcTlhgGKJeLZ3RnoToBjdhBclEN6JjRv-nxWOrfYJn99-j4tv7d1fnH8vLzx8uzs8uS1PTKpdMaLsAa3lTSbBgOW9sZ9qWUeh7UbGu4S2zwjQS9AITneC1ELWUHbAF9HpxVFxsdfugr9UKC9DxTgXt1CYR4qB0zM54UMzKihvBJaW6kn0rpW502zao2PaiE6j1Zqu1mrsReoMdiNrviO7-mdxSDeFWtRWOA5UocHwvEMPNDCmrEZsC3usJwpwUb2hTt23drL1ePIBehzniO6xRrK64qNr2D2rQeAE32YC-Zi2qzhCFQ0bF2vb0Hyg8PYzO4OBah_kdwskOATEZfuRBzympi69fdrF8izUxpBTB_u4Ho2q9C2q7Cwp3QW12QTVIkg9IBsd1PRdYmfP_o_4ClccSrA
CitedBy_id crossref_primary_10_1016_j_foodchem_2024_142496
crossref_primary_10_1016_j_arabjc_2023_105430
crossref_primary_10_1016_j_jep_2023_117563
crossref_primary_10_3390_ijms25158290
crossref_primary_10_1038_s41598_023_43638_1
crossref_primary_10_3390_genes15030293
crossref_primary_10_1186_s12870_023_04532_0
crossref_primary_10_1186_s12870_024_05975_9
crossref_primary_10_3390_cimb45110578
Cites_doi 10.1186/s12870-016-0967-1
10.3390/plants8100410
10.1111/cla.12191
10.1021/jf4037547
10.1371/journal.pone.0013431
10.1186/1471-2148-6-32
10.1038/srep08348
10.1093/nar/gkz238
10.1111/nph.13261
10.1016/j.ygeno.2019.04.010
10.1093/oxfordjournals.molbev.a026236
10.1002/ece3.8151
10.1038/s41598-018-29114-1
10.3389/fphar.2021.609059
10.1186/s40659-020-00289-0
10.1371/journal.pone.0016371
10.1146/annurev-genet-120215-035349
10.1093/nar/gkx391
10.1371/journal.pone.0000508
10.1093/nar/15.3.1281
10.1016/j.saa.2021.120054
10.3389/fpls.2019.00531
10.1093/bioinformatics/15.5.426
10.1093/oso/9780195135848.001.0001
10.1002/tax.602017
10.3732/ajb.93.2.278
10.1093/nar/gkz345
10.1016/j.ympev.2019.106713
10.1002/pca.3033
10.1093/database/bau107
10.3389/fpls.2018.01453
10.1371/journal.pone.0074394
10.1016/j.ympev.2013.04.023
10.1016/j.saa.2021.119798
10.1016/j.fsigen.2019.102188
10.1111/jse.12310
10.1111/jse.12427
10.3390/molecules22020249
10.1105/tpc.13.3.645
10.1007/s11684-017-0504-0
10.1371/journal.pone.0222707
10.1371/journal.pone.0035071
10.1093/bioinformatics/btx198
10.1080/23802359.2020.1791005
10.3389/fpls.2020.593984
10.1111/tpj.13491
10.1186/s12870-019-1870-3
10.1080/23802359.2021.1930598
10.1038/s41598-020-76699-7
10.3389/fpls.2017.00590
10.1016/j.ijbiomac.2021.05.117
10.3390/plants8110476
10.1007/s11033-016-4023-x
10.3390/molecules24224124
10.3389/fgene.2018.00374
10.1186/s43141-021-00188-1
10.1016/j.bse.2020.104005
10.3389/fpls.2021.723622
10.1093/molbev/msx248
10.1371/journal.pone.0092501
10.1093/molbev/msw054
10.1039/D0FO01997F
10.1186/s12864-019-6215-y
10.1186/s12864-021-07807-8
10.1371/journal.pone.0144701
10.3389/fpls.2020.600354
10.1111/brv.12104
10.1016/j.ympev.2020.106948
10.1038/s41598-018-20381-6
10.1002/tax.603001
10.1016/j.ympev.2011.10.019
10.3389/fpls.2018.01989
10.1186/1471-2229-8-59
10.3389/fphar.2020.550497
10.1007/s00709-020-01585-y
10.1016/j.bse.2010.12.011
10.3390/genes8010013
10.12705/654.4
10.1080/23802359.2019.1673234
10.1016/j.saa.2020.118380
10.3389/fpls.2016.00341
10.1073/pnas.0905845106
10.1093/nar/gkp337
10.1007/s10722-014-0210-6
10.1016/j.ygeno.2019.08.016
10.1371/journal.pone.0057607
10.1080/14620316.2017.1373039
10.3390/plants10071288
10.1007/s00606-008-0105-0
10.1186/s12870-018-1429-8
10.1016/j.foodchem.2017.04.037
10.1007/s11103-011-9762-4
10.3732/ajb.0900218
10.1186/1756-0500-7-77
10.1016/j.jep.2021.113836
10.1038/s41598-020-77661-3
10.1038/nrg2899
10.1371/journal.pone.0229181
10.1371/journal.pone.0008613
10.1093/molbev/mst010
10.1007/s00425-019-03150-1
10.1016/j.jep.2020.113247
10.1016/j.jhazmat.2020.122364
10.1080/23802359.2020.1775508
ContentType Journal Article
Copyright COPYRIGHT 2022 BioMed Central Ltd.
2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2022. The Author(s).
The Author(s) 2022
Copyright_xml – notice: COPYRIGHT 2022 BioMed Central Ltd.
– notice: 2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2022. The Author(s).
– notice: The Author(s) 2022
DBID AAYXX
CITATION
ISR
3V.
7QP
7QR
7SS
7TK
7U7
7X7
7XB
88E
8AO
8FD
8FE
8FH
8FI
8FJ
8FK
ABUWG
AEUYN
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
C1K
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
HCIFZ
K9.
LK8
M0S
M1P
M7P
P64
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
RC3
7X8
5PM
DOA
DOI 10.1186/s12864-022-08755-7
DatabaseName CrossRef
Gale In Context: Science
ProQuest Central (Corporate)
Calcium & Calcified Tissue Abstracts
Chemoreception Abstracts
Entomology Abstracts (Full archive)
Neurosciences Abstracts
Toxicology Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
Technology Research Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni Edition)
ProQuest One Sustainability
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central Korea
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
ProQuest Biological Science Collection
Health & Medical Collection (Alumni Edition)
Medical Database
Biological Science Database
Biotechnology and BioEngineering Abstracts
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
Genetics Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
Publicly Available Content Database
ProQuest Central Student
Technology Research Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Pharma Collection
Environmental Sciences and Pollution Management
ProQuest Central
ProQuest One Applied & Life Sciences
ProQuest One Sustainability
ProQuest Health & Medical Research Collection
Genetics Abstracts
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Health & Medical Research Collection
Biological Science Collection
Chemoreception Abstracts
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest Biological Science Collection
Toxicology Abstracts
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
Neurosciences Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Entomology Abstracts
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
Engineering Research Database
ProQuest One Academic
Calcium & Calcified Tissue Abstracts
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList
Publicly Available Content Database



MEDLINE - Academic
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1471-2164
EndPage 31
ExternalDocumentID oai_doaj_org_article_1f842c62800a48d988a7a9972569d6b6
PMC9412808
A715147068
10_1186_s12864_022_08755_7
GeographicLocations China
GeographicLocations_xml – name: China
GrantInformation_xml – fundername: ;
  grantid: 2021JKZKTS020B
– fundername: ;
  grantid: LGF22H280005
GroupedDBID ---
0R~
23N
2WC
2XV
53G
5VS
6J9
7X7
88E
8AO
8FE
8FH
8FI
8FJ
AAFWJ
AAHBH
AAJSJ
AASML
AAYXX
ABDBF
ABUWG
ACGFO
ACGFS
ACIHN
ACIWK
ACPRK
ACUHS
ADBBV
ADUKV
AEAQA
AENEX
AEUYN
AFKRA
AFPKN
AFRAH
AHBYD
AHMBA
AHYZX
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AMKLP
AMTXH
AOIJS
BAPOH
BAWUL
BBNVY
BCNDV
BENPR
BFQNJ
BHPHI
BMC
BPHCQ
BVXVI
C6C
CCPQU
CITATION
CS3
DIK
DU5
E3Z
EAD
EAP
EAS
EBD
EBLON
EBS
EMB
EMK
EMOBN
ESX
F5P
FYUFA
GROUPED_DOAJ
GX1
HCIFZ
HMCUK
IAO
IGS
IHR
INH
INR
ISR
ITC
KQ8
LK8
M1P
M48
M7P
M~E
O5R
O5S
OK1
OVT
P2P
PGMZT
PHGZM
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
RBZ
RNS
ROL
RPM
RSV
SBL
SOJ
SV3
TR2
TUS
U2A
UKHRP
W2D
WOQ
WOW
XSB
PMFND
3V.
7QP
7QR
7SS
7TK
7U7
7XB
8FD
8FK
AZQEC
C1K
DWQXO
FR3
GNUQQ
K9.
P64
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQUKI
RC3
7X8
PUEGO
5PM
ID FETCH-LOGICAL-c504t-16af3eff2748efef227fbc9910edd641b7291f6c78ea3d64b62566588be13eda3
IEDL.DBID DOA
ISSN 1471-2164
IngestDate Wed Aug 27 01:16:14 EDT 2025
Thu Aug 21 14:33:26 EDT 2025
Sun Aug 24 03:58:17 EDT 2025
Fri Jul 25 09:58:22 EDT 2025
Tue Jun 17 21:49:48 EDT 2025
Tue Jun 10 20:40:07 EDT 2025
Fri Jun 27 03:57:16 EDT 2025
Thu Apr 24 22:59:44 EDT 2025
Tue Jul 01 00:39:20 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
License Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c504t-16af3eff2748efef227fbc9910edd641b7291f6c78ea3d64b62566588be13eda3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
OpenAccessLink https://doaj.org/article/1f842c62800a48d988a7a9972569d6b6
PMID 36028808
PQID 2715426499
PQPubID 44682
PageCount 31
ParticipantIDs doaj_primary_oai_doaj_org_article_1f842c62800a48d988a7a9972569d6b6
pubmedcentral_primary_oai_pubmedcentral_nih_gov_9412808
proquest_miscellaneous_2707599576
proquest_journals_2715426499
gale_infotracmisc_A715147068
gale_infotracacademiconefile_A715147068
gale_incontextgauss_ISR_A715147068
crossref_primary_10_1186_s12864_022_08755_7
crossref_citationtrail_10_1186_s12864_022_08755_7
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2022-08-26
PublicationDateYYYYMMDD 2022-08-26
PublicationDate_xml – month: 08
  year: 2022
  text: 2022-08-26
  day: 26
PublicationDecade 2020
PublicationPlace London
PublicationPlace_xml – name: London
PublicationTitle BMC genomics
PublicationYear 2022
Publisher BioMed Central Ltd
BioMed Central
BMC
Publisher_xml – name: BioMed Central Ltd
– name: BioMed Central
– name: BMC
References N Zhang (8755_CR64) 2015; 10
S Habib (8755_CR66) 2017; 26
SY Yin (8755_CR16) 2021; 10
G Raman (8755_CR44) 2016; 7
QR Wang (8755_CR69) 2021; 149
MH Yin (8755_CR99) 2018; 19
S-L Chen (8755_CR101) 2010; 5
LL Miao (8755_CR88) 2019; 24
L Zhang (8755_CR79) 2021; 12
YC Zhang (8755_CR91) 2020; 89
S Beier (8755_CR118) 2017; 33
X Peng (8755_CR12) 2016; 43
J Guo (8755_CR87) 2017; 232
YH Wang (8755_CR1) 2015; 206
WP Dong (8755_CR52) 2015; 5
J Xiang (8755_CR48) 2020; 5
D Tröndle (8755_CR80) 2010; 97
YJ Li (8755_CR15) 2014; 24
W Dong (8755_CR104) 2012; 7
R Millen (8755_CR42) 2001; 13
L He (8755_CR46) 2017; 22
WB Xu (8755_CR82) 2020; 10
HL Fang (8755_CR28) 2010; 38
XL Yu (8755_CR45) 2019; 8
XY Yang (8755_CR83) 2017; 11
JY Yang (8755_CR84) 2019; 14
SR Lee (8755_CR19) 2019; 20
XD Xu (8755_CR32) 2021; 11
TA Hall (8755_CR122) 1999; 41
CH Ng (8755_CR27) 2020; 44
SM Li (8755_CR94) 2020; 51
PM Sharp (8755_CR115) 1987; 15
XX Shen (8755_CR55) 2021; 23
LM Lu (8755_CR60) 2018; 34
WJ Long (8755_CR89) 2021; 258
Z Huang (8755_CR93) 2007; 31
QY Tian (8755_CR41) 2019; 4
GY Xu (8755_CR43) 2021; 258
L Gu (8755_CR40) 2020; 5
VT Ho (8755_CR57) 2021; 19
A Soejima (8755_CR62) 2006; 93
WJ Kress (8755_CR102) 2007; 2
LC Jiao (8755_CR73) 2018; 8
LC Jiao (8755_CR74) 2019; 250
V Kumar (8755_CR92) 2018; 8
Plant Working Group CBOL (8755_CR100) 2009; 106
QJ Li (8755_CR76) 2020; 10
M Nei (8755_CR53) 2000
J Wen (8755_CR63) 2013; 8
LC Shi (8755_CR112) 2019; 47
GA Palidwor (8755_CR30) 2010; 5
J Rozas (8755_CR121) 2017; 34
MD Logacheva (8755_CR50) 2008; 8
KM Neubig (8755_CR72) 2009; 277
ZQ Wu (8755_CR22) 2012; 62
J Qian (8755_CR35) 2013; 8
MF Abdullah (8755_CR51) 2019; 112
SU Islam (8755_CR71) 2021; 23
S Kumar (8755_CR114) 2016; 33
GA de Groot (8755_CR103) 2011; 6
MC Qiu (8755_CR4) 2019; 35
K Katoh (8755_CR120) 2013; 30
JJ Doyle (8755_CR110) 1987; 19
MH Yin (8755_CR98) 2018; 30
Q Chu (8755_CR6) 2020; 393
Y Sun (8755_CR8) 2013; 61
T Ji (8755_CR9) 2021; 264
PT Chen (8755_CR67) 2011; 63
A Ali (8755_CR116) 2018; 17
Z-G Liu (8755_CR13) 2021; 32
YJ Qu (8755_CR56) 2018; 9
RY Zhu (8755_CR2) 2020; 11
C Luo (8755_CR23) 2021; 22
CW Jiao (8755_CR95) 2021; 261
MX Wang (8755_CR36) 2016; 8
WY Hu (8755_CR3) 2021; 271
M Tillich (8755_CR111) 2017; 45
H Ren (8755_CR61) 2011; 60
F-M Zhou (8755_CR7) 2021; 12
CM Gao (8755_CR78) 2018; 9
JB Plotkin (8755_CR31) 2011; 12
DR Zhou (8755_CR96) 2020; 238
G Guo (8755_CR90) 2018; 93
DN Zhao (8755_CR77) 2019; 144
S Wicke (8755_CR39) 2011; 76
J Wen (8755_CR37) 2018; 56
S Kurtz (8755_CR117) 1999; 15
B Li (8755_CR34) 2020; 53
RK Jansen (8755_CR58) 2006; 6
PB Pelser (8755_CR11) 2016; 65
JP Mower (8755_CR119) 2009; 37
M Zhu (8755_CR106) 2021; 11
H Daniell (8755_CR18) 2016; 50
ZF Chu (8755_CR65) 2018; 56
I Shahzadi (8755_CR20) 2020; 112
AS Wang (8755_CR26) 2018; 9
YT Li (8755_CR75) 2021; 11
Z Yang (8755_CR54) 2000; 17
J Tonti-Filippini (8755_CR38) 2017; 90
SB Zhang (8755_CR86) 2021; 32
SR Downie (8755_CR49) 1991; 45
HB Liu (8755_CR29) 2020; 499
YX Zhang (8755_CR25) 2017; 17
S Greiner (8755_CR113) 2019; 47
WX Gong (8755_CR17) 2021; 183
Q Chen (8755_CR81) 2020; 15
A Kapil (8755_CR108) 2014; 2014
S Iram (8755_CR21) 2019; 8
B Zhu (8755_CR109) 2015; 37
X Huang (8755_CR47) 2021; 6
ZY Ma (8755_CR59) 2021; 154
X Li (8755_CR70) 2015; 90
PT Chen (8755_CR10) 2011; 60
X Peng (8755_CR14) 2015; 62
HT Zhou (8755_CR85) 2002; 37
YH Wang (8755_CR97) 2018; 18
JJ Yang (8755_CR105) 2019; 10
YL Li (8755_CR5) 2020; 11
LM Lu (8755_CR68) 2013; 68
SL Song (8755_CR107) 2014; 7
J Lee (8755_CR33) 2014; 9
CH Gu (8755_CR24) 2019; 19
References_xml – volume: 149
  start-page: 5
  year: 2021
  ident: 8755_CR69
  publication-title: Genetica.
– volume: 35
  start-page: 305963
  year: 2019
  ident: 8755_CR4
  publication-title: Chin J Clin Pharmacol
– volume: 17
  start-page: 34
  year: 2017
  ident: 8755_CR25
  publication-title: BMC Plant Biol
  doi: 10.1186/s12870-016-0967-1
– volume: 8
  start-page: 410
  year: 2019
  ident: 8755_CR45
  publication-title: Plants (Basel)
  doi: 10.3390/plants8100410
– volume: 41
  start-page: 95
  year: 1999
  ident: 8755_CR122
  publication-title: Nucleic Acids Symp Ser
– volume: 37
  start-page: 383
  year: 2002
  ident: 8755_CR85
  publication-title: Yao xue xue bao = Acta pharmaceutica Sinica
– volume: 34
  start-page: 57
  year: 2018
  ident: 8755_CR60
  publication-title: Cladistics.
  doi: 10.1111/cla.12191
– volume: 61
  start-page: 10507
  year: 2013
  ident: 8755_CR8
  publication-title: J Agric Food Chem
  doi: 10.1021/jf4037547
– volume: 5
  start-page: e13431
  year: 2010
  ident: 8755_CR30
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0013431
– volume: 6
  start-page: 32
  year: 2006
  ident: 8755_CR58
  publication-title: BMC Evol Biol
  doi: 10.1186/1471-2148-6-32
– volume: 5
  start-page: 8348
  year: 2015
  ident: 8755_CR52
  publication-title: Sci Rep
  doi: 10.1038/srep08348
– volume: 47
  start-page: W59
  year: 2019
  ident: 8755_CR113
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkz238
– volume: 206
  start-page: 852
  year: 2015
  ident: 8755_CR1
  publication-title: New Phytol
  doi: 10.1111/nph.13261
– volume: 112
  start-page: 581
  year: 2019
  ident: 8755_CR51
  publication-title: Genomics.
  doi: 10.1016/j.ygeno.2019.04.010
– volume: 17
  start-page: 32
  year: 2000
  ident: 8755_CR54
  publication-title: Mol Biol Evol
  doi: 10.1093/oxfordjournals.molbev.a026236
– volume: 11
  start-page: 14327
  year: 2021
  ident: 8755_CR106
  publication-title: Ecol Evol
  doi: 10.1002/ece3.8151
– volume: 8
  start-page: 10714
  year: 2018
  ident: 8755_CR92
  publication-title: Sci Rep
  doi: 10.1038/s41598-018-29114-1
– volume: 12
  start-page: 609059
  year: 2021
  ident: 8755_CR7
  publication-title: Front Pharmacol
  doi: 10.3389/fphar.2021.609059
– volume: 53
  start-page: 21
  year: 2020
  ident: 8755_CR34
  publication-title: Biol Res
  doi: 10.1186/s40659-020-00289-0
– volume: 63
  start-page: 313
  year: 2011
  ident: 8755_CR67
  publication-title: Gardens Bull Singapore
– volume: 6
  start-page: e16371
  year: 2011
  ident: 8755_CR103
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0016371
– volume: 50
  start-page: 595
  year: 2016
  ident: 8755_CR18
  publication-title: Annu Rev Genet
  doi: 10.1146/annurev-genet-120215-035349
– volume: 45
  start-page: W6
  year: 2017
  ident: 8755_CR111
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkx391
– volume: 2
  start-page: e508
  year: 2007
  ident: 8755_CR102
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0000508
– volume: 15
  start-page: 1281
  year: 1987
  ident: 8755_CR115
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/15.3.1281
– volume: 261
  start-page: 120054
  year: 2021
  ident: 8755_CR95
  publication-title: Spectrochim Acta A Mol Biomol Spectrosc
  doi: 10.1016/j.saa.2021.120054
– volume: 10
  start-page: 531
  year: 2019
  ident: 8755_CR105
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2019.00531
– volume: 32
  start-page: 3025
  year: 2021
  ident: 8755_CR13
  publication-title: Analysis.
– volume: 15
  start-page: 426
  year: 1999
  ident: 8755_CR117
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/15.5.426
– volume-title: Molecular evolution and phylogenetics
  year: 2000
  ident: 8755_CR53
  doi: 10.1093/oso/9780195135848.001.0001
– volume: 60
  start-page: 499
  year: 2011
  ident: 8755_CR10
  publication-title: Taxon.
  doi: 10.1002/tax.602017
– volume: 93
  start-page: 278
  year: 2006
  ident: 8755_CR62
  publication-title: Am J Bot
  doi: 10.3732/ajb.93.2.278
– volume: 47
  start-page: W65
  year: 2019
  ident: 8755_CR112
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkz345
– volume: 144
  start-page: 106713
  year: 2019
  ident: 8755_CR77
  publication-title: Mol Phylogenet Evol
  doi: 10.1016/j.ympev.2019.106713
– volume: 32
  start-page: 899
  year: 2021
  ident: 8755_CR86
  publication-title: Phytochem Anal
  doi: 10.1002/pca.3033
– volume: 19
  start-page: 1222
  year: 2018
  ident: 8755_CR99
  publication-title: J Plant Genet Resour
– volume: 2014
  start-page: bau107
  year: 2014
  ident: 8755_CR108
  publication-title: Database
  doi: 10.1093/database/bau107
– volume: 9
  start-page: 1453
  year: 2018
  ident: 8755_CR56
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2018.01453
– volume: 8
  start-page: e74394
  year: 2013
  ident: 8755_CR63
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0074394
– volume: 68
  start-page: 502
  year: 2013
  ident: 8755_CR68
  publication-title: Mol Phylogenet Evol
  doi: 10.1016/j.ympev.2013.04.023
– volume: 258
  start-page: 119798
  year: 2021
  ident: 8755_CR89
  publication-title: Spectrochim Acta A Mol Biomol Spectrosc
  doi: 10.1016/j.saa.2021.119798
– volume: 44
  start-page: 102188
  year: 2020
  ident: 8755_CR27
  publication-title: Forensic Sci Int Genet
  doi: 10.1016/j.fsigen.2019.102188
– volume: 56
  start-page: 273
  year: 2018
  ident: 8755_CR65
  publication-title: J Syst Evol
  doi: 10.1111/jse.12310
– volume: 56
  start-page: 262
  year: 2018
  ident: 8755_CR37
  publication-title: J Syst Evol
  doi: 10.1111/jse.12427
– volume: 22
  start-page: 249
  year: 2017
  ident: 8755_CR46
  publication-title: Molecules.
  doi: 10.3390/molecules22020249
– volume: 13
  start-page: 645
  year: 2001
  ident: 8755_CR42
  publication-title: Plant Cell
  doi: 10.1105/tpc.13.3.645
– volume: 11
  start-page: 203
  year: 2017
  ident: 8755_CR83
  publication-title: Front Med
  doi: 10.1007/s11684-017-0504-0
– volume: 14
  start-page: e0222707
  year: 2019
  ident: 8755_CR84
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0222707
– volume: 7
  start-page: e35071
  issue: 4
  year: 2012
  ident: 8755_CR104
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0035071
– volume: 33
  start-page: 2583
  year: 2017
  ident: 8755_CR118
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btx198
– volume: 5
  start-page: 2855
  year: 2020
  ident: 8755_CR48
  publication-title: Mitochondrial DNA B Resour
  doi: 10.1080/23802359.2020.1791005
– volume: 11
  start-page: 593984
  year: 2021
  ident: 8755_CR75
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2020.593984
– volume: 90
  start-page: 808
  year: 2017
  ident: 8755_CR38
  publication-title: Plant J
  doi: 10.1111/tpj.13491
– volume: 19
  start-page: 281
  year: 2019
  ident: 8755_CR24
  publication-title: BMC Plant Biol
  doi: 10.1186/s12870-019-1870-3
– volume: 6
  start-page: 1745
  year: 2021
  ident: 8755_CR47
  publication-title: Mitochondrial DNA B Resour.
  doi: 10.1080/23802359.2021.1930598
– volume: 10
  start-page: 19781
  year: 2020
  ident: 8755_CR76
  publication-title: Sci Rep
  doi: 10.1038/s41598-020-76699-7
– volume: 23
  start-page: 100305
  year: 2021
  ident: 8755_CR71
  publication-title: Don J Appl Res Med Aroma
– volume: 26
  start-page: 590
  year: 2017
  ident: 8755_CR66
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2017.00590
– volume: 183
  start-page: 1540
  year: 2021
  ident: 8755_CR17
  publication-title: Int J Biol Macromol
  doi: 10.1016/j.ijbiomac.2021.05.117
– volume: 8
  start-page: 476
  year: 2019
  ident: 8755_CR21
  publication-title: Plants
  doi: 10.3390/plants8110476
– volume: 17
  start-page: 3030
  year: 2018
  ident: 8755_CR116
  publication-title: Bioinformatics
– volume: 43
  start-page: 785
  year: 2016
  ident: 8755_CR12
  publication-title: Mol Biol Rep
  doi: 10.1007/s11033-016-4023-x
– volume: 24
  start-page: 4124
  year: 2019
  ident: 8755_CR88
  publication-title: Molecules.
  doi: 10.3390/molecules24224124
– volume: 30
  start-page: 1839
  year: 2018
  ident: 8755_CR98
  publication-title: Acta Agric Zhejiangensis
– volume: 9
  start-page: 374
  year: 2018
  ident: 8755_CR26
  publication-title: Front Genet
  doi: 10.3389/fgene.2018.00374
– volume: 19
  start-page: 93
  year: 2021
  ident: 8755_CR57
  publication-title: J Genet Eng Biotechnol
  doi: 10.1186/s43141-021-00188-1
– volume: 89
  start-page: 104005
  year: 2020
  ident: 8755_CR91
  publication-title: Biochem Syst Ecol
  doi: 10.1016/j.bse.2020.104005
– volume: 12
  start-page: 723622
  year: 2021
  ident: 8755_CR79
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2021.723622
– volume: 34
  start-page: 3299
  year: 2017
  ident: 8755_CR121
  publication-title: Mol Biol Evol
  doi: 10.1093/molbev/msx248
– volume: 9
  start-page: e92501
  year: 2014
  ident: 8755_CR33
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0092501
– volume: 33
  start-page: 1870
  year: 2016
  ident: 8755_CR114
  publication-title: Mol Biol Evol
  doi: 10.1093/molbev/msw054
– volume: 11
  start-page: 9776
  year: 2020
  ident: 8755_CR5
  publication-title: Food Funct
  doi: 10.1039/D0FO01997F
– volume: 20
  start-page: 833
  year: 2019
  ident: 8755_CR19
  publication-title: BMC Genomics
  doi: 10.1186/s12864-019-6215-y
– volume: 22
  start-page: 571
  year: 2021
  ident: 8755_CR23
  publication-title: BMC Genomics
  doi: 10.1186/s12864-021-07807-8
– volume: 51
  start-page: 197
  year: 2020
  ident: 8755_CR94
  publication-title: Chin Tradition Herb Drugs
– volume: 10
  start-page: e0144701
  year: 2015
  ident: 8755_CR64
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0144701
– volume: 499
  start-page: 1
  year: 2020
  ident: 8755_CR29
  publication-title: J Genet
– volume: 11
  start-page: 600354
  year: 2021
  ident: 8755_CR32
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2020.600354
– volume: 90
  start-page: 157
  year: 2015
  ident: 8755_CR70
  publication-title: Biol Rev
  doi: 10.1111/brv.12104
– volume: 154
  start-page: 106948
  year: 2021
  ident: 8755_CR59
  publication-title: Mol Phylogenet Evol
  doi: 10.1016/j.ympev.2020.106948
– volume: 8
  start-page: 1945
  year: 2018
  ident: 8755_CR73
  publication-title: Sci Rep
  doi: 10.1038/s41598-018-20381-6
– volume: 60
  start-page: 629
  year: 2011
  ident: 8755_CR61
  publication-title: Taxon.
  doi: 10.1002/tax.603001
– volume: 62
  start-page: 573
  year: 2012
  ident: 8755_CR22
  publication-title: Mol Phylogenet Evol
  doi: 10.1016/j.ympev.2011.10.019
– volume: 9
  start-page: 1989
  year: 2018
  ident: 8755_CR78
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2018.01989
– volume: 31
  start-page: 759
  year: 2007
  ident: 8755_CR93
  publication-title: J Zhejiang Chin Med Univ.
– volume: 8
  start-page: 59
  year: 2008
  ident: 8755_CR50
  publication-title: BMC Plant Biol
  doi: 10.1186/1471-2229-8-59
– volume: 11
  start-page: 550497
  year: 2020
  ident: 8755_CR2
  publication-title: Front Pharmacol
  doi: 10.3389/fphar.2020.550497
– volume: 45
  start-page: 1245
  year: 1991
  ident: 8755_CR49
  publication-title: Evolution.
– volume: 19
  start-page: 11
  year: 1987
  ident: 8755_CR110
  publication-title: Phytochem Bull
– volume: 258
  start-page: 559
  year: 2021
  ident: 8755_CR43
  publication-title: Protoplasma.
  doi: 10.1007/s00709-020-01585-y
– volume: 38
  start-page: 1204
  year: 2010
  ident: 8755_CR28
  publication-title: Biochem Syst Ecol
  doi: 10.1016/j.bse.2010.12.011
– volume: 8
  start-page: 13
  year: 2016
  ident: 8755_CR36
  publication-title: Genes.
  doi: 10.3390/genes8010013
– volume: 65
  start-page: 739
  year: 2016
  ident: 8755_CR11
  publication-title: Taxon.
  doi: 10.12705/654.4
– volume: 4
  start-page: 3370
  year: 2019
  ident: 8755_CR41
  publication-title: Mitochondrial DNA B Resour.
  doi: 10.1080/23802359.2019.1673234
– volume: 23
  start-page: 275-9+325
  year: 2021
  ident: 8755_CR55
  publication-title: Modern Chin Med
– volume: 238
  start-page: 118380
  year: 2020
  ident: 8755_CR96
  publication-title: Spectrochim Acta A Mol Biomol Spectrosc
  doi: 10.1016/j.saa.2020.118380
– volume: 7
  start-page: 341
  year: 2016
  ident: 8755_CR44
  publication-title: Front Plant Sci
  doi: 10.3389/fpls.2016.00341
– volume: 106
  start-page: 12794
  year: 2009
  ident: 8755_CR100
  publication-title: Proc Natl Acad Sci
  doi: 10.1073/pnas.0905845106
– volume: 37
  start-page: W253
  year: 2009
  ident: 8755_CR119
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkp337
– volume: 62
  start-page: 1069
  year: 2015
  ident: 8755_CR14
  publication-title: Genet Resour Crop Evol
  doi: 10.1007/s10722-014-0210-6
– volume: 112
  start-page: 1454
  year: 2020
  ident: 8755_CR20
  publication-title: Genomics.
  doi: 10.1016/j.ygeno.2019.08.016
– volume: 8
  start-page: e57607
  year: 2013
  ident: 8755_CR35
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0057607
– volume: 93
  start-page: 416
  year: 2018
  ident: 8755_CR90
  publication-title: J Hortic Sci Biotechnol
  doi: 10.1080/14620316.2017.1373039
– volume: 24
  start-page: 40
  year: 2014
  ident: 8755_CR15
  publication-title: J Zhejiang Chin Med Univ
– volume: 10
  start-page: 1288
  year: 2021
  ident: 8755_CR16
  publication-title: Plants.
  doi: 10.3390/plants10071288
– volume: 277
  start-page: 75
  year: 2009
  ident: 8755_CR72
  publication-title: Plant Syst Evol
  doi: 10.1007/s00606-008-0105-0
– volume: 18
  start-page: 208
  year: 2018
  ident: 8755_CR97
  publication-title: BMC Plant Biol
  doi: 10.1186/s12870-018-1429-8
– volume: 232
  start-page: 552
  year: 2017
  ident: 8755_CR87
  publication-title: Food Chem
  doi: 10.1016/j.foodchem.2017.04.037
– volume: 76
  start-page: 273
  year: 2011
  ident: 8755_CR39
  publication-title: Plant Mol Biol
  doi: 10.1007/s11103-011-9762-4
– volume: 97
  start-page: 1168
  year: 2010
  ident: 8755_CR80
  publication-title: Am J Bot
  doi: 10.3732/ajb.0900218
– volume: 7
  start-page: 77
  year: 2014
  ident: 8755_CR107
  publication-title: BMC Res Notes
  doi: 10.1186/1756-0500-7-77
– volume: 271
  start-page: 113866
  year: 2021
  ident: 8755_CR3
  publication-title: J Ethnopharmacol
  doi: 10.1016/j.jep.2021.113836
– volume: 10
  start-page: 20782
  year: 2020
  ident: 8755_CR82
  publication-title: Sci Rep
  doi: 10.1038/s41598-020-77661-3
– volume: 37
  start-page: 914
  year: 2015
  ident: 8755_CR109
  publication-title: Acta Agric Univ Jiangxiensis
– volume: 12
  start-page: 43
  year: 2011
  ident: 8755_CR31
  publication-title: Nat Rev Genet
  doi: 10.1038/nrg2899
– volume: 15
  start-page: e0229181
  year: 2020
  ident: 8755_CR81
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0229181
– volume: 5
  start-page: e8613
  year: 2010
  ident: 8755_CR101
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0008613
– volume: 30
  start-page: 772
  year: 2013
  ident: 8755_CR120
  publication-title: Mol Biol Evol
  doi: 10.1093/molbev/mst010
– volume: 250
  start-page: 94
  year: 2019
  ident: 8755_CR74
  publication-title: Planta
  doi: 10.1007/s00425-019-03150-1
– volume: 264
  start-page: 113247
  year: 2021
  ident: 8755_CR9
  publication-title: J Ethnopharmacol
  doi: 10.1016/j.jep.2020.113247
– volume: 393
  start-page: 122364
  year: 2020
  ident: 8755_CR6
  publication-title: J Hazard Mater
  doi: 10.1016/j.jhazmat.2020.122364
– volume: 5
  start-page: 2423
  year: 2020
  ident: 8755_CR40
  publication-title: Mitochondrial DNA B Resour.
  doi: 10.1080/23802359.2020.1775508
SSID ssj0017825
Score 2.4409482
Snippet Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae...
Background Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the...
Abstract Background Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs...
SourceID doaj
pubmedcentral
proquest
gale
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Enrichment Source
Index Database
StartPage 1
SubjectTerms Anticancer properties
Apoptosis
Bar codes
Biomarkers
Chloroplast genome
Chloroplasts
Comparative analysis
Deoxyribonucleic acid
Discrimination
Distribution
DNA
DNA barcoding
DNA barcoing markers
Flavonoids
Gene order
Gene sequencing
Genes
Genetic aspects
Genomes
Genomics
Geographical distribution
Geographical origins
Germplasm
Herbal medicine
Inflammation
Medicinal plants
Methods
Molecular structure
Morphology
Nucleotide diversity
Origins
Phylogenetic relationships
Phylogenetics
Phylogeny
Proteins
rRNA
Taxonomy
Tetrastigma hemsleyanum
tRNA
Tumors
Vitaceae
SummonAdditionalLinks – databaseName: Health & Medical Collection
  dbid: 7X7
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lj9MwELZgERIXxFN0WZBBSIAg2iR1bIcLKo_VgsQeYBf1Zvm5rUSTskkP_Fd-DDOJ0xKQ9lbF4zTOvJ3xN4Q8YymzvNQmkTnjCStMAJVyOkkDeGfO0pB3IElfTvjxGfs8L-Zxw62JZZWDTewMtast7pEf5gKcPXjvsny7_plg1yj8uhpbaFwl1xC6DEu6xHybcGXg_YrhoIzkhw3YYs4SrF9HHPciESNn1GH2_2-Z_62W_Mv9HN0iN2PcSGc9o2-TK766Q673nSR_3SW_gd20Kw-HIJjaBWTh9RoC45YiCOvKN7QO9NTDnRFUY6Xpwq9wu1pXmxV98X3Zauu1f0nxtAkdmqa0FNs2gFji5K7R9hu6Gtrp0h55dnPhX1O7gxCnOqKcwA9H3a4kCe_x4WRGDWhW7eCBIFqmy7aBB-xRs1FaaN-ni-JZ4b7fGMrNPXJ29PH0_XESGzcktkhZm2Rch6kPATJe6YMPeS6CsRCJpt45zjIDEX0WuBXS6ylcMJCEcQiFpPHZ1Ds9vU_2qrryDwgtIMBwmXCFMVOI3LzRloE_FR5RespUTkg2cFDZiGqOzTV-qC67kVz1XFfAddVxXYkJebWds-4xPS6lfoeCsaVEPO7uQn1xrqJ6qyxIllueQ_itmXSllFpoPJNc8NJxwyfkKYqVQsSNCkt6zvWmadSnb1_VDAQ7YyLlsJbnkSjUsAar4wkJeBMI0jWiPBhRgkmw4-FBelU0SY3aKdCEPNkO40wss6t8vUEaiCDLEnLQCREjqR8tfzxSLRcdLHnJ4N2lcv_yP39IbuS9BiY5PyB7IKv-EcR1rXncKe8fS0FQuA
  priority: 102
  providerName: ProQuest
– databaseName: Scholars Portal Journals: Open Access
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3da9RAEF9qRfBF_MTTKqsIKpqa5Da7G0Hk_ChVaB-0J31b9rN30EvqJQf2f_WPcSYfd0aLT74d2dmQ3ZnJ_CY3-xtCnrCYWZ5rE8mU8YhlJoBLOR3FAaIzZ3FIG5Kkg0O-P2Wfj7PjLdK3O-o2sLowtcN-UtPl6e6P7-dvweHfNA4v-asK3rGcRViXjvzsWSQukcsQmQQ66gHb_KsA0TDrD85cOG8QnBoO_7_f1H9WT_4Wjvauk2sdjqSTVvE3yJYvbpIrbWfJ81vkJ6ifNuXiAIqpnUFWXp4BUK4pkrIufEXLQI883BlJNhaazvwCP1_rYrWgz77Na2299s8pnj6hfROVmmIbBzBTnNw03n5NF317Xdoy0a6W_iW1G0pxqjvWE_jhqNuUKOE9PhxOqAFPKx08EKBnOq8reMCWRRuth7Z9uyieHW77j6Ed3SbTvY9H7_ejrpFDZLOY1VHCdRj7ECADlj74kKYiGAvINPbOcZYYQPhJ4FZIr8dwwUBSxgEaSeOTsXd6fIdsF2Xh7xKaAeBwiXCZMWNAct5oyyC-Co-sPXksRyTpNahsx3KOzTZOVZPtSK5arSvQumq0rsSIvFjPOWs5Pv4p_Q4NYy2J_NzNhXJ5ojp3V0mQLLU8BTiumXS5lFpoPKOc8dxxw0fkMZqVQgaOAkt8TvSqqtSnr1_URAAIYyLmsJannVAoYQ1WdycmYCeQtGsguTOQhFeEHQ731qt6D1MpDCMczvMRebQexplYdlf4coUygCjzHHLSEREDqx8sfzhSzGcNTXnOYO9iee9_7Nd9cjVt_TRK-Q7ZBov2DwAN1uZh4-K_ADTLYEU
  priority: 102
  providerName: Scholars Portal
Title The complete chloroplast genomes of Tetrastigma hemsleyanum (Vitaceae) from different regions of China: molecular structure, comparative analysis and development of DNA barcodes for its geographical origin discrimination
URI https://www.proquest.com/docview/2715426499
https://www.proquest.com/docview/2707599576
https://pubmed.ncbi.nlm.nih.gov/PMC9412808
https://doaj.org/article/1f842c62800a48d988a7a9972569d6b6
Volume 23
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3db9MwELdgCIkXxKcIjMogJEAQLUkd2-Gtg00DaRUaG-qbZTv2WokmE0kf-F_5Y7iLk24BCV54qar4HPnj7Ptde_c7Ql6whFleaBPLjPGY5cbDkSp1nHiwzpwlPutIko7n_OiMfVrkiyulvjAmLNADh4XbS71kmeUZABvNZFlIqYXGbM-cFyU3Hdk22LzBmer_PwC7lw8pMpLvNXALcxZj5DoyuOexGJmhjq3_zzv59zjJK4bn8A653SNGOgsjvUuuueoeuRlqSP64T37CRtMuMBzgL7VL8L_rC4DELUX61bVraO3pqYM3I53GWtOlW-MP1brarOmrr6tWW6fda4p5JnQol9JSLNgAComduxLb7-h6KKRLA-fs5rt7S-0leTjVPb8JfClpeRmMhO_4MJ9RA2eqLmFAgJPpqm1ggIEvG_WEhgpdFLOEQ6Ux1JgH5Ozw4PT9UdyXbIhtnrA2Trn2U-c9-LrSeeezTHhjAYMmriw5Sw1g-dRzK6TTU3hgwP3iAIKkcenUlXr6kOxUdeUeEZoDtChTUebGTAGzOaMtA0sqHPLzFImMSDrsoLI9nzmW1fimOr9GchV2XcGuq27XlYjIm22fi8Dm8VfpfVSMrSQycXcPQD9Vr5_qX_oZkeeoVgq5NioM5jnXm6ZRH7-cqJkAuMVEwmEuL3shX8McrO5zI2AlkJ5rJLk7koTLwI6bB-1V_WXUqAyaEfgWRUSebZuxJwbYVa7eoAxgx6IA7zMiYqT1o-mPW6rVsiMkLxisXSIf_4_1ekJuZeGcxhnfJTug0e4p4L7WTMh1sRATcmP_YP75ZNIdePg8ZvIXkRJbTg
linkProvider Directory of Open Access Journals
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1tb9MwELZGJwRfEK-iMMAgECCIlhfHSZAQ6timjm0VGh3aN2M79lqJJmVJhfan-EX8GO7y0hKQ9m3fqvjsxrnzvSR3zxHynLlM80QqJ_YZd1ioLBypVDquBevMmWv9CiTpcMSHx-zTSXiyRn61tTCYVtnqxEpRp7nGd-SbfgTGHqx3knyY_3CwaxR-XW1baNRisW_Of0LIVrzf2wb-vvD93Z3xx6HTdBVwdOiy0vG4tIGxFsKx2FhjfT-ySoOb5Jo05cxT4G56lusoNjKACwoiBA52OlbGC0wqA1j3CllnAYQyPbK-tTP6fLT8bgH2NmxLc2K-WYD258zBjHlEjg-dqGP-qi4B_9uCf_Mz_zJ4uzfJjcZTpYNatG6RNZPdJlfr3pXnd8hvEDBaJaSD2031BOL-fA6ueEkR9nVmCppbOjawMsJ4zCSdmBm-IJfZYkZffZ2WUhtpXlOsb6Ftm5aSYqMIOAg4uWrt_Y7O2ga-tMa6XZyZt1SvQMupbHBV4EdK01USFK6xPRpQBUzLU7gh8M_ptCzgBmucbpRPWncGo1idXHc4Q0m9S44vhan3SC_LM3Of0BBcmtSL0lCpAHxFo6RmYMEjg7hAiRv3iddyUOgGRx3beXwXVTwVc1FzXQDXRcV1EfXJm-WceY0iciH1FgrGkhIRwKsL-dmpaBSK8GzMfM19cPgli9MkjmUksQo65EnKFe-TZyhWAjE-MkwiOpWLohB7X47EAI6SxyKXw15eNkQ2hz1o2dRkwJNAWLAO5UaHEpSQ7g630isaJViI1ZHtk6fLYZyJiX2ZyRdIAz5rkkDU2ydRR-o72--OZNNJBYSeMHh2bvzg4j9_Qq4Nx4cH4mBvtP-QXPfr0-j4fIP0QG7NI_AqS_W4OcqUfLts7fEHoLKQBw
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+complete+chloroplast+genomes+of+Tetrastigma+hemsleyanum+%28Vitaceae%29+from+different+regions+of+China%3A+molecular+structure%2C+comparative+analysis+and+development+of+DNA+barcodes+for+its+geographical+origin+discrimination&rft.jtitle=BMC+genomics&rft.au=Shujie+Dong&rft.au=Manjia+Zhou&rft.au=Jinxing+Zhu&rft.au=Qirui+Wang&rft.date=2022-08-26&rft.pub=BMC&rft.eissn=1471-2164&rft.volume=23&rft.issue=1&rft.spage=1&rft.epage=31&rft_id=info:doi/10.1186%2Fs12864-022-08755-7&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_1f842c62800a48d988a7a9972569d6b6
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1471-2164&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1471-2164&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1471-2164&client=summon