Characterization of NpgA, a 4′-phosphopantetheinyl transferase of Aspergillus nidulans, and evidence of its involvement in fungal growth and formation of conidia and cleistothecia for development

• Published in: The journal of microbiology Vol. 53; no. 1; pp. 21 - 31
• Main Authors: Kim, Jung-Mi, Song, Ha-Yeon, Choi, Hyo-Jin, So, Kum-Kang, Kim, Dae-Hyuk, Chae, Keon-Sang, Han, Dong-Min, Jahng, Kwang-Yeop
• Format: Journal Article
• Language: English
• Published: Heidelberg The Microbiological Society of Korea 01.01.2015; Springer Nature B.V; 한국미생물학회
• Subjects: Adenosine Diphosphate - analogs & derivatives; Aspergillus nidulans; Aspergillus nidulans - enzymology; Aspergillus nidulans - genetics; Aspergillus nidulans - physiology; Aspergillus nidulans - ultrastructure; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biomedical and Life Sciences; Biosynthesis; Cell Wall - metabolism; E coli; Enzymes; Escherichia; Fatty acids; Filtrate; Fungal Proteins - genetics; Fungal Proteins - metabolism; Fungi; Gene Expression Regulation, Fungal; Genomics and Molecular Biology; Life Sciences; Metabolism; Metabolites; Microbial Genetics; Microbiology; Molecular biology; Mutation; Penicillin; Phenotype; Pigmentation; Pigmentation - genetics; Pigments; Proteins; Reproduction, Asexual; Saccharomyces cerevisiae; Saccharomyces cerevisiae - genetics; Secondary metabolites; Sequence Analysis, DNA; Spores, Fungal - growth & development; Thionucleotides; Transferases (Other Substituted Phosphate Groups) - genetics; Transferases (Other Substituted Phosphate Groups) - metabolism; 생물학; South Korea; phosphopantetheinyl transferase; development; metabolite

The null pigmentation mutant ( npgA1 ) in Aspergillus nidulans results in a phenotype with colorless organs, decreased branching growth, delayed of asexual spore development, and aberrant cell wall structure. The npgA gene was isolated from A. nidulans to investigate these pleiomorphic phenomena of...