A novel approach to determining pulmonary valve replacement timing in repaired tetralogy of Fallot patients

• Published in: International journal of cardiology congenital heart disease Vol. 21; p. 100597
• Main Authors: Delaney, Laura, Browne, Andrew, Veldtman, Gruschen R., Huang, Sihong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2025; Elsevier
• Subjects: Cardiovascular; Original

Here we propose a novel approach to determine a patient-specific optimal time for pulmonary valve replacement (PVR) in patients with repaired tetralogy of Fallot (rTOF) based on a mathematical technique known as optimal stopping theory. We outline, in a theoretical framework, how we would apply the...