Characterization of Insulin Adsorption Behavior of Dialyzer Membranes Used in Hemodialysis

• Published in: Artificial organs Vol. 35; no. 4; pp. 398 - 403
• Main Authors: Abe, Masanori, Okada, Kazuyoshi, Ikeda, Kazuya, Matsumoto, Shiro, Soma, Masayoshi, Matsumoto, Koichi
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.04.2011
• Subjects: Adsorption; Aged; Aged, 80 and over; Alloys - chemistry; Cellulose - analogs & derivatives; Cellulose - chemistry; Diabetes mellitus; Diabetes Mellitus - blood; Equipment Design; Female; Hemodialysis; High-flux dialyzer; Humans; Insulin; Insulin - blood; Insulin - isolation & purification; Male; Membranes, Artificial; Middle Aged; Polyesters - chemistry; Polymers - chemistry; Renal Dialysis - instrumentation; Sulfones - chemistry

Although it has been reported that plasma insulin is removed by hemodialysis (HD), the mechanism for this has not been elucidated. We investigated the mechanism of insulin removal during HD treatment and the characteristics of insulin removal with three high‐flux membranes. In our in vivo study, 20...