Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects - Yamazaki, Takao; Desai, Amit; Goldwater, Ronald; Han, David; Lasseter, Kenneth C.; Howieson, Corrie; Akhtar, Shahzad; Kowalski, Donna; Lademacher, Christopher; Rammelsberg, Diane; Townsend, Robert (Clinical pharmacology in drug development, 2017)
Keywords: Adult; Area Under Curve; atorvastatin; Atorvastatin Calcium - administration & dosage; digoxin; Digoxin - administration & dosage; Drug dosages; Female; Healthy Volunteers; Humans; isavuconazole; Male; Membrane Transport Proteins - metabolism; metformin; Metformin - administration & dosage; methotrexate; Methotrexate - administration & dosage; Middle Aged; Nitriles - administration & dosage; Nitriles - pharmacokinetics; Original Manuscript; Pyridines - administration & dosage; Pyridines - pharmacokinetics; Triazoles - administration & dosage; Triazoles - pharmacokinetics; Young Adult; metformin; methotrexate; isavuconazole; digoxin; atorvastatin