scRNA-seq analysis of cells comprising the amphioxus notochord

• Published in: Developmental biology Vol. 508; pp. 24 - 37
• Main Authors: Takahashi, Hiroki, Hisata, Kanako, Iguchi, Rin, Kikuchi, Sakura, Ogasawara, Michio, Satoh, Noriyuki
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2024
• Subjects: Amphioxus notochord; Animals; Brachyury; Constituent cells; ectoderm; endoderm; Erinaceidae; gene expression; Gene Expression Regulation, Developmental - genetics; Hedgehog; Hedgehog Proteins - genetics; hybridization; Lancelets; mesoderm; myofibrils; Müller cells; nerve tissue; Notochord; Phylogeny; scRNA-seq analysis; sequence analysis; Single-Cell Gene Expression Analysis; Urochordata; ventral nerve cord; Vertebrates; Brachyury; Amphioxus notochord; Constituent cells; Müller cells; Hedgehog; scRNA-seq analysis

Cephalochordates occupy a key phylogenetic position for deciphering the origin and evolution of chordates, since they diverged earlier than urochordates and vertebrates. The notochord is the most prominent feature of chordates. The amphioxus notochord features coin-shaped cells bearing myofibrils. N...