The PI3K/Akt, p38MAPK, and JAK2/STAT3 signaling pathways mediate the protection of SO2 against acute lung injury induced by limb ischemia/reperfusion in rats - Zhao, Yan-Rui; Wang, Dong; Liu, Yang; Shan, Lei; Zhou, Jun-Lin (The journal of physiological sciences, 2016)
Keywords: Acute lung injury; Acute Lung Injury - etiology; Acute Lung Injury - physiopathology; Animals; Extremities - blood supply; Inhibitor; Interleukins - physiology; Ischemia - complications; Ischemia - physiopathology; Ischemia/reperfusion; JAK2/STAT3; Janus Kinase 2 - physiology; Male; MAP Kinase Signaling System - physiology; Na2SO3/NaHSO3; Oncogene Protein v-akt - physiology; Original Paper; p38 MAPK; Phosphatidylinositol 3-Kinases - physiology; PI3K/Akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury - complications; Reperfusion Injury - physiopathology; Signal Transduction - physiology; STAT3 Transcription Factor - physiology; Sulfur dioxide; Sulfur Dioxide - metabolism; Acute lung injury; Na2SO3/NaHSO3; JAK2/STAT3; Inhibitor; Ischemia/reperfusion; p38 MAPK; Sulfur dioxide; PI3K/Akt