Author HANTSCHEL, Oliver
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Issue 2
Keywords Chromosomal aberration
Drug combination
Treatment resistance
Philadelphia positive acute lymphoblastic leukemia
Hematology
Enzyme
Transferases
Non-specific serine/threonine protein kinase
Malignant hemopathy
Philadelphia chromosome
Abnormal chromosome C9
Allosteric inhibitor
bcr gene
Lymphoproliferative syndrome
C-Onc gene
Abnormal chromosome G22
Abnormal chromosome
Hybrid gene
Cancer
Chromosome translocation
Language English
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PublicationTitle Haematologica (Roma)
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PublicationYear 2012
Publisher Ferrata Storti Foundation
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References 21264348 - PLoS One. 2011;6(1):e15929
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16415863 - Nat Chem Biol. 2006 Feb;2(2):95-102
19798092 - Leukemia. 2009 Dec;23(12):2242-7
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22058195 - Haematologica. 2012 Feb;97(2):251-7
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StartPage 157
SubjectTerms Biological and medical sciences
Chromosome aberrations
Fusion Proteins, bcr-abl - antagonists & inhibitors
Hematologic and hematopoietic diseases
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical genetics
Medical sciences
Pyrimidines - pharmacology
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Title Allosteric BCR-ABL inhibitors in Philadelphia chromosome-positive acute lymphoblastic leukemia: novel opportunities for drug combinations to overcome resistance
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