Comparison of five automated serum and whole blood folate assays

• Published in: American journal of clinical pathology Vol. 120; no. 1; pp. 121 - 126
• Main Authors: OWEN, William E, ROBERTS, William L
• Format: Journal Article
• Language: English
• Published: Chicago, IL American Society of Clinical Pathologists 01.07.2003
• Subjects: Biological and medical sciences; Blood Chemical Analysis - methods; Clinical Laboratory Techniques; Erythrocytes - chemistry; Folic Acid - blood; Hemolysis; Humans; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Miscellaneous. Technology; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Radioimmunoassay; Reproducibility of Results; Human; Biochemical analysis; Method comparison; Folate; Hemolysate; Imprecision; Whole blood; Automatic analyzer; Linearity; Clinical biology; Serum; Technique; Comparative study; Quantitative analysis

Serum and whole blood folate measurements are used to establish folate deficiency. Most methods used in clinical laboratories are automated, nonistopic methods that use folate-binding protein. Linearity, imprecision, and method comparison studies, including serum and whole blood hemolysates, were pe...