Bacterial biogeography of the human digestive tract

We present bacterial biogeography as sampled from the human gastrointestinal tract of four healthy subjects. This study generated >32 million paired-end sequences of bacterial 16S rRNA genes (V3 region) representing >95,000 unique operational taxonomic units (OTUs; 97% similarity clusters), wi...

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Published in	Scientific reports Vol. 1; no. 1; p. 170
Main Authors	Stearns, Jennifer C., Lynch, Michael D. J., Senadheera, Dilani B., Tenenbaum, Howard C., Goldberg, Michael B., Cvitkovitch, Dennis G., Croitoru, Kenneth, Moreno-Hagelsieb, Gabriel, Neufeld, Josh D.
Format	Journal Article
Language	English
Published	London Nature Publishing Group UK 25.11.2011 Nature Publishing Group
Subjects	631/114 631/158/670 631/326/171 Adult Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Biodiversity Biogeography Biopsy Colon Duodenum Female Gastrointestinal tract Gastrointestinal Tract - microbiology Humanities and Social Sciences Humans Male Metagenome - genetics Microbial activity Microflora multidisciplinary Organ Specificity Phylogeny RNA, Bacterial - genetics RNA, Ribosomal, 16S - genetics rRNA 16S Science Stomach
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Abstract	We present bacterial biogeography as sampled from the human gastrointestinal tract of four healthy subjects. This study generated >32 million paired-end sequences of bacterial 16S rRNA genes (V3 region) representing >95,000 unique operational taxonomic units (OTUs; 97% similarity clusters), with >99% Good's coverage for all samples. The highest OTU richness and phylogenetic diversity was found in the mouth samples. The microbial communities of multiple biopsy sites within the colon were highly similar within individuals and largely distinct from those in stool. Within an individual, OTU overlap among broad site definitions (mouth, stomach/duodenum, colon and stool) ranged from 32–110 OTUs, 25 of which were common to all individuals and included OTUs affiliated with Faecalibacterium prasnitzii and the TM7 phylum. This first comprehensive characterization of the abundant and rare microflora found along the healthy human digestive tract represents essential groundwork to investigate further how the human microbiome relates to health and disease.
AbstractList	We present bacterial biogeography as sampled from the human gastrointestinal tract of four healthy subjects. This study generated >32 million paired-end sequences of bacterial 16S rRNA genes (V3 region) representing >95,000 unique operational taxonomic units (OTUs; 97% similarity clusters), with >99% Good's coverage for all samples. The highest OTU richness and phylogenetic diversity was found in the mouth samples. The microbial communities of multiple biopsy sites within the colon were highly similar within individuals and largely distinct from those in stool. Within an individual, OTU overlap among broad site definitions (mouth, stomach/duodenum, colon and stool) ranged from 32–110 OTUs, 25 of which were common to all individuals and included OTUs affiliated with Faecalibacterium prasnitzii and the TM7 phylum. This first comprehensive characterization of the abundant and rare microflora found along the healthy human digestive tract represents essential groundwork to investigate further how the human microbiome relates to health and disease. We present bacterial biogeography as sampled from the human gastrointestinal tract of four healthy subjects. This study generated >32 million paired-end sequences of bacterial 16S rRNA genes (V3 region) representing >95,000 unique operational taxonomic units (OTUs; 97% similarity clusters), with >99% Good's coverage for all samples. The highest OTU richness and phylogenetic diversity was found in the mouth samples. The microbial communities of multiple biopsy sites within the colon were highly similar within individuals and largely distinct from those in stool. Within an individual, OTU overlap among broad site definitions (mouth, stomach/duodenum, colon and stool) ranged from 32-110 OTUs, 25 of which were common to all individuals and included OTUs affiliated with Faecalibacterium prasnitzii and the TM7 phylum. This first comprehensive characterization of the abundant and rare microflora found along the healthy human digestive tract represents essential groundwork to investigate further how the human microbiome relates to health and disease.We present bacterial biogeography as sampled from the human gastrointestinal tract of four healthy subjects. This study generated >32 million paired-end sequences of bacterial 16S rRNA genes (V3 region) representing >95,000 unique operational taxonomic units (OTUs; 97% similarity clusters), with >99% Good's coverage for all samples. The highest OTU richness and phylogenetic diversity was found in the mouth samples. The microbial communities of multiple biopsy sites within the colon were highly similar within individuals and largely distinct from those in stool. Within an individual, OTU overlap among broad site definitions (mouth, stomach/duodenum, colon and stool) ranged from 32-110 OTUs, 25 of which were common to all individuals and included OTUs affiliated with Faecalibacterium prasnitzii and the TM7 phylum. This first comprehensive characterization of the abundant and rare microflora found along the healthy human digestive tract represents essential groundwork to investigate further how the human microbiome relates to health and disease. We present bacterial biogeography as sampled from the human gastrointestinal tract of four healthy subjects. This study generated >32 million paired-end sequences of bacterial 16S rRNA genes (V3 region) representing >95,000 unique operational taxonomic units (OTUs; 97% similarity clusters), with >99% Good's coverage for all samples. The highest OTU richness and phylogenetic diversity was found in the mouth samples. The microbial communities of multiple biopsy sites within the colon were highly similar within individuals and largely distinct from those in stool. Within an individual, OTU overlap among broad site definitions (mouth, stomach/duodenum, colon and stool) ranged from 32-110 OTUs, 25 of which were common to all individuals and included OTUs affiliated with Faecalibacterium prasnitzii and the TM7 phylum. This first comprehensive characterization of the abundant and rare microflora found along the healthy human digestive tract represents essential groundwork to investigate further how the human microbiome relates to health and disease.
ArticleNumber	170
Author	Lynch, Michael D. J. Moreno-Hagelsieb, Gabriel Cvitkovitch, Dennis G. Senadheera, Dilani B. Stearns, Jennifer C. Tenenbaum, Howard C. Goldberg, Michael B. Croitoru, Kenneth Neufeld, Josh D.
Author_xml	– sequence: 1 givenname: Jennifer C. surname: Stearns fullname: Stearns, Jennifer C. organization: Department of Biology, University of Waterloo, Farncombe Family Digestive Health Research Institute, Faculty of Health Sciences, McMaster University – sequence: 2 givenname: Michael D. J. surname: Lynch fullname: Lynch, Michael D. J. organization: Department of Biology, University of Waterloo, Department of Biology, Wilfrid Laurier University – sequence: 3 givenname: Dilani B. surname: Senadheera fullname: Senadheera, Dilani B. organization: Faculty of Dentistry, University of Toronto – sequence: 4 givenname: Howard C. surname: Tenenbaum fullname: Tenenbaum, Howard C. organization: Faculty of Dentistry, University of Toronto – sequence: 5 givenname: Michael B. surname: Goldberg fullname: Goldberg, Michael B. organization: Faculty of Dentistry, University of Toronto – sequence: 6 givenname: Dennis G. surname: Cvitkovitch fullname: Cvitkovitch, Dennis G. organization: Faculty of Dentistry, University of Toronto – sequence: 7 givenname: Kenneth surname: Croitoru fullname: Croitoru, Kenneth organization: Department of Medicine, University of Toronto, Zane Cohen Center for Digestive Diseases, Mount Sinai Hospital – sequence: 8 givenname: Gabriel surname: Moreno-Hagelsieb fullname: Moreno-Hagelsieb, Gabriel organization: Department of Biology, Wilfrid Laurier University – sequence: 9 givenname: Josh D. surname: Neufeld fullname: Neufeld, Josh D. organization: Department of Biology, University of Waterloo
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/22355685$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1177/154405910308200503 10.1093/bioinformatics/btq461 10.1128/JB.00542-10 10.1186/gb-2011-12-5-r50 10.1371/journal.pbio.0050177 10.1073/pnas.0605127103 10.1073/pnas.1002601107 10.1007/s11894-010-0111-6 10.1038/nature08821 10.1038/nmeth.f.303 10.1371/journal.pone.0002836 10.1053/j.gastro.2010.08.049 10.1126/science.1104816 10.1073/pnas.0504978102 10.1073/pnas.0607077104 10.1073/pnas.0306398101 10.1038/nature07540 10.1126/science.1171700 10.1038/ismej.2010.30 10.1111/j.1462-2920.2009.02051.x 10.1099/jmm.0.47719-0 10.1093/bioinformatics/btl158 10.1073/pnas.0807920105 10.1053/j.gastro.2010.06.063 10.1126/science.1110591 10.1093/molbev/msp077 10.1016/j.mimet.2009.09.012 10.1128/JCM.41.2.558-563.2003 10.1126/science.1179721 10.1128/AEM.03006-05 10.1016/j.cell.2005.05.007 10.1073/pnas.0506655103 10.1111/j.1462-2920.2010.02193.x 10.1007/s00248-010-9712-8 10.1053/j.gastro.2011.04.052 10.1371/journal.pone.0021280 10.1128/JCM.01272-07 10.1128/AEM.00062-07 10.1128/AEM.02772-10 10.1126/science.1177486 10.1073/pnas.0804812105 10.1016/j.anaerobe.2005.05.001 10.1177/154405910808701104 10.1128/JB.183.12.3770-3783.2001 10.1161/CIRCULATIONAHA.104.511998 10.1016/S0140-6736(03)12489-0 10.1111/j.1600-051X.2010.01679.x 10.1128/aem.59.3.695-700.1993 10.1371/journal.pone.0015406 10.1007/978-0-387-98141-3 10.1038/ismej.2011.85
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References	Sears (CR28) 2005; 11 Fierer, Hamady, Lauber, Knight (CR19) 2008; 105 Price, Dehal, Arkin (CR53) 2009; 26 Ley (CR26) 2005; 102 Muyzer, de Waal, Uitterlinden (CR47) 1993; 59 Costello (CR17) 2009; 326 Edgar (CR48) 2010; 26 CR30 Beck (CR3) 2005; 112 Kumar (CR39) 2003; 82 Lazarevic (CR9) 2009; 79 Vijay-Kumar (CR5) 2010; 328 Wang, Garrity, Tiedje, Cole (CR45) 2007; 73 Guarner, Malagelada (CR34) 2003; 361 Bik (CR29) 2010; 4 Bercik (CR6) 2011; 141 Bercik (CR7) 2010; 139 Kunin, Engelbrektson, Ochman, Hugenholtz (CR33) 2010; 12 Kuehbacher (CR41) 2008; 57 CR49 Caporaso (CR52) 2010; 7 CR46 Keijser (CR13) 2008; 87 Dominguez-Bello (CR11) 2010; 107 Dinis (CR36) 2011; 6 DeSantis (CR51) 2006; 72 Wade (CR15) 2011; 38 Fredricks, Fiedler, Thomas, Oakley, Marrazzo (CR42) 2007; 45 Gao, Tseng, Pei, Blaser (CR43) 2007; 104 Qin (CR35) 2010; 464 Sogin (CR44) 2006; 103 Li, Godzik (CR24) 2006; 22 Caporaso (CR20) 2011; 12 Eckburg (CR27) 2005; 308 CR54 Mazmanian, Liu, Tzianabos, Kasper (CR1) 2005; 122 Paster (CR37) 2001; 183 Sokol (CR4) 2008; 105 CR50 Huse, Welch, Morrison, Sogin (CR23) 2010; 12 Willing (CR14) 2010; 139 Lawson, Coyle (CR32) 2010; 12 Bäckhed, Ley, Sonnenburg, Peterson, Gordon (CR2) 2005; 307 Andersson (CR21) 2008; 3 Ling (CR31) 2010; 60 Kazor (CR38) 2003; 41 Pei (CR40) 2004; 101 Grice (CR18) 2009; 324 CR25 Dewhirst (CR8) 2010; 192 Bik (CR16) 2006; 103 Turnbaugh (CR12) 2009; 457 Bartram, Lynch, Stearns, Moreno-Hagelsieb, Neufeld (CR22) 2011; 77 Palmer, Bik, DiGiulio, Relman, Brown (CR10) 2007; 5 V Lazarevic (BFsrep00170_CR9) 2009; 79 CE Kazor (BFsrep00170_CR38) 2003; 41 Z Ling (BFsrep00170_CR31) 2010; 60 BFsrep00170_CR50 DN Fredricks (BFsrep00170_CR42) 2007; 45 EK Costello (BFsrep00170_CR17) 2009; 326 TZ DeSantis (BFsrep00170_CR51) 2006; 72 EA Grice (BFsrep00170_CR18) 2009; 324 BFsrep00170_CR54 F Guarner (BFsrep00170_CR34) 2003; 361 JG Caporaso (BFsrep00170_CR20) 2011; 12 W Li (BFsrep00170_CR24) 2006; 22 B Willing (BFsrep00170_CR14) 2010; 139 EM Bik (BFsrep00170_CR29) 2010; 4 SK Mazmanian (BFsrep00170_CR1) 2005; 122 C Palmer (BFsrep00170_CR10) 2007; 5 P Bercik (BFsrep00170_CR6) 2011; 141 JG Caporaso (BFsrep00170_CR52) 2010; 7 FE Dewhirst (BFsrep00170_CR8) 2010; 192 BJF Keijser (BFsrep00170_CR13) 2008; 87 F Bäckhed (BFsrep00170_CR2) 2005; 307 BFsrep00170_CR49 BFsrep00170_CR46 N Fierer (BFsrep00170_CR19) 2008; 105 RD Lawson (BFsrep00170_CR32) 2010; 12 T Kuehbacher (BFsrep00170_CR41) 2008; 57 J Qin (BFsrep00170_CR35) 2010; 464 Z Gao (BFsrep00170_CR43) 2007; 104 MG Dominguez-Bello (BFsrep00170_CR11) 2010; 107 H Sokol (BFsrep00170_CR4) 2008; 105 S Huse (BFsrep00170_CR23) 2010; 12 BJ Paster (BFsrep00170_CR37) 2001; 183 BFsrep00170_CR30 JM Dinis (BFsrep00170_CR36) 2011; 6 Q Wang (BFsrep00170_CR45) 2007; 73 Z Pei (BFsrep00170_CR40) 2004; 101 ML Sogin (BFsrep00170_CR44) 2006; 103 P Turnbaugh (BFsrep00170_CR12) 2009; 457 RE Ley (BFsrep00170_CR26) 2005; 102 WG Wade (BFsrep00170_CR15) 2011; 38 M Vijay-Kumar (BFsrep00170_CR5) 2010; 328 G Muyzer (BFsrep00170_CR47) 1993; 59 AK Bartram (BFsrep00170_CR22) 2011; 77 CL Sears (BFsrep00170_CR28) 2005; 11 V Kunin (BFsrep00170_CR33) 2010; 12 MN Price (BFsrep00170_CR53) 2009; 26 RC Edgar (BFsrep00170_CR48) 2010; 26 P Bercik (BFsrep00170_CR7) 2010; 139 BFsrep00170_CR25 JD Beck (BFsrep00170_CR3) 2005; 112 PS Kumar (BFsrep00170_CR39) 2003; 82 EM Bik (BFsrep00170_CR16) 2006; 103 AF Andersson (BFsrep00170_CR21) 2008; 3 PB Eckburg (BFsrep00170_CR27) 2005; 308 21460107 - Appl Environ Microbiol. 2011 Jun;77(11):3846-52 20709691 - Bioinformatics. 2010 Oct 1;26(19):2460-1 20614117 - Microb Ecol. 2010 Oct;60(3):677-90 11371542 - J Bacteriol. 2001 Jun;183(12):3770-83 20600016 - Gastroenterology. 2010 Dec;139(6):2102-2112.e1 20203013 - Science. 2010 Apr 9;328(5975):228-31 15831718 - Science. 2005 Jun 10;308(5728):1635-8 21624126 - Genome Biol. 2011;12(5):R50 18936492 - Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16731-6 19043404 - Nature. 2009 Jan 22;457(7228):480-4 19478181 - Science. 2009 May 29;324(5931):1190-2 15016918 - Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4250-5 16033867 - Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11070-5 20816835 - Gastroenterology. 2010 Dec;139(6):1844-1854.e1 21048977 - PLoS One. 2010;5(10):e15406 19892944 - Science. 2009 Dec 18;326(5960):1694-7 20203603 - Nature. 2010 Mar 4;464(7285):59-65 16820507 - Appl Environ Microbiol. 2006 Jul;72(7):5069-72 16701579 - Anaerobe. 2005 Oct;11(5):247-51 16407106 - Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):732-7 21683077 - Gastroenterology. 2011 Aug;141(2):599-609, 609.e1-3 20336157 - ISME J. 2010 Aug;4(8):962-74 16880384 - Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12115-20 17594176 - PLoS Biol. 2007 Jul;5(7):e177 12574246 - J Clin Microbiol. 2003 Feb;41(2):558-63 21716308 - ISME J. 2012 Jan;6(1):46-56 20383131 - Nat Methods. 2010 May;7(5):335-6 19377059 - Mol Biol Evol. 2009 Jul;26(7):1641-50 21323699 - J Clin Periodontol. 2011 Mar;38 Suppl 11:7-16 16731699 - Bioinformatics. 2006 Jul 1;22(13):1658-9 17687006 - J Clin Microbiol. 2007 Oct;45(10):3270-6 16009137 - Cell. 2005 Jul 15;122(1):107-18 19796657 - J Microbiol Methods. 2009 Dec;79(3):266-71 12709498 - J Dent Res. 2003 May;82(5):338-44 19018031 - J Med Microbiol. 2008 Dec;57(Pt 12):1569-76 18946007 - J Dent Res. 2008 Nov;87(11):1016-20 17586664 - Appl Environ Microbiol. 2007 Aug;73(16):5261-7 15790844 - Science. 2005 Mar 25;307(5717):1915-20 19725865 - Environ Microbiol. 2010 Jan;12(1):118-23 20532707 - Curr Gastroenterol Rep. 2010 Aug;12(4):259-62 19004758 - Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17994-9 15983248 - Circulation. 2005 Jul 5;112(1):19-24 7683183 - Appl Environ Microbiol. 1993 Mar;59(3):695-700 17293459 - Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2927-32 18665274 - PLoS One. 2008;3(7):e2836 21701585 - PLoS One. 2011;6(6):e21280 20566857 - Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11971-5 12583961 - Lancet. 2003 Feb 8;361(9356):512-9 20656903 - J Bacteriol. 2010 Oct;192(19):5002-17 20236171 - Environ Microbiol. 2010 Jul;12(7):1889-98
References_xml	– volume: 82 start-page: 338 year: 2003 end-page: 344 ident: CR39 article-title: New bacterial species associated with chronic periodontitis publication-title: J. Dent. Res. doi: 10.1177/154405910308200503 – volume: 26 start-page: 2460 year: 2010 end-page: 2461 ident: CR48 article-title: Search and clustering orders of magnitude faster than BLAST publication-title: Bioinformatics doi: 10.1093/bioinformatics/btq461 – ident: CR49 – volume: 192 start-page: 5002 year: 2010 end-page: 5017 ident: CR8 article-title: The human oral microbiome publication-title: J. Bacteriol. doi: 10.1128/JB.00542-10 – volume: 12 start-page: R50 year: 2011 ident: CR20 article-title: Moving pictures of the human microbiome publication-title: Genome Biol. doi: 10.1186/gb-2011-12-5-r50 – volume: 5 start-page: e177 year: 2007 ident: CR10 article-title: Development of the human infant intestinal microbiota publication-title: PLoS Biol. doi: 10.1371/journal.pbio.0050177 – volume: 103 start-page: 12115 year: 2006 end-page: 12120 ident: CR44 article-title: Microbial diversity in the deep sea and the underexplored “rare biosphere” publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0605127103 – volume: 59 start-page: 695 year: 1993 end-page: 700 ident: CR47 article-title: Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA publication-title: Appl. Environ. Microbiol. – volume: 107 start-page: 11971 year: 2010 end-page: 11975 ident: CR11 article-title: Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.1002601107 – volume: 12 start-page: 259 year: 2010 end-page: 262 ident: CR32 article-title: The noncolonic microbiome: does it really matter? publication-title: Curr. Gastroenterol. Rep. doi: 10.1007/s11894-010-0111-6 – volume: 464 start-page: 59 year: 2010 end-page: 65 ident: CR35 article-title: A human gut microbial gene catalogue established by metagenomic sequencing publication-title: Nature doi: 10.1038/nature08821 – volume: 7 start-page: 335 year: 2010 end-page: 336 ident: CR52 article-title: QIIME allows analysis of high-throughput community sequencing data publication-title: Nat. Methods doi: 10.1038/nmeth.f.303 – ident: CR54 – ident: CR25 – volume: 3 start-page: e2836 year: 2008 ident: CR21 article-title: Comparative analysis of human gut microbiota by barcoded pyrosequencing publication-title: PLoS ONE doi: 10.1371/journal.pone.0002836 – volume: 139 start-page: 1844 year: 2010 end-page: 1854 ident: CR14 article-title: A pyrosequencing study in twins shows that GI microbial profiles vary with inflammatory bowel disease phenotypes publication-title: Gastroenterology doi: 10.1053/j.gastro.2010.08.049 – volume: 307 start-page: 1915 year: 2005 end-page: 1920 ident: CR2 article-title: Host-bacterial mutualism in the human intestine publication-title: Science doi: 10.1126/science.1104816 – volume: 102 start-page: 11070 year: 2005 end-page: 11075 ident: CR26 article-title: Obesity alters gut microbial ecology publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0504978102 – ident: CR46 – volume: 104 start-page: 2927 year: 2007 end-page: 2932 ident: CR43 article-title: Molecular analysis of human forearm superficial skin bacterial biota publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0607077104 – volume: 101 start-page: 4250 year: 2004 end-page: 4255 ident: CR40 article-title: Bacterial biota in the human distal esophagus publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0306398101 – volume: 457 start-page: 480 year: 2009 end-page: 484 ident: CR12 article-title: A core gut microbiome in obese and lean twins publication-title: Nature doi: 10.1038/nature07540 – ident: CR50 – volume: 324 start-page: 1190 year: 2009 end-page: 1192 ident: CR18 article-title: Topographical and temporal diversity of the human skin microbiome publication-title: Science doi: 10.1126/science.1171700 – volume: 4, start-page: 962 year: 2010 end-page: 974 ident: CR29 article-title: Bacterial diversity in the oral cavity of 10 healthy individuals publication-title: ISME J doi: 10.1038/ismej.2010.30 – volume: 12 start-page: 118 year: 2010 end-page: 123 ident: CR33 article-title: Wrinkles in the rare biosphere: pyrosequencing errors can lead to artificial inflation of diversity estimates publication-title: Environ. Microbiol. doi: 10.1111/j.1462-2920.2009.02051.x – volume: 57 start-page: 1569 year: 2008 end-page: 1576 ident: CR41 article-title: Intestinal TM7 bacterial phylogenies in active inflammatory bowel disease publication-title: J. Med. Microbiol. doi: 10.1099/jmm.0.47719-0 – volume: 22 start-page: 1658 year: 2006 end-page: 1659 ident: CR24 article-title: Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences publication-title: Bioinformatics doi: 10.1093/bioinformatics/btl158 – volume: 105 start-page: 17994 year: 2008 end-page: 17999 ident: CR19 article-title: The influence of sex, handedness and washing on the diversity of hand surface bacteria publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0807920105 – volume: 139 start-page: 2102 year: 2010 end-page: 2112 ident: CR7 article-title: Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice publication-title: Gastroenterology doi: 10.1053/j.gastro.2010.06.063 – volume: 308 start-page: 1635 year: 2005 end-page: 1638 ident: CR27 article-title: Diversity of the human intestinal microbial flora publication-title: Science doi: 10.1126/science.1110591 – volume: 26 start-page: 1641 year: 2009 end-page: 1650 ident: CR53 article-title: FastTree: computing large minimum evolution trees with profiles instead of a distance matrix publication-title: Mol. Biol. Evol. doi: 10.1093/molbev/msp077 – ident: CR30 – volume: 79 start-page: 266 year: 2009 end-page: 271 ident: CR9 article-title: Metagenomic study of the oral microbiota by Illumina high-throughput sequencing publication-title: J. Microbiol. Meth. doi: 10.1016/j.mimet.2009.09.012 – volume: 41 start-page: 558 year: 2003 end-page: 563 ident: CR38 article-title: Diversity of bacterial populations on the tongue dorsa of patients with halitosis and healthy patients publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.41.2.558-563.2003 – volume: 328 start-page: 228 year: 2010 end-page: 231 ident: CR5 article-title: Metabolic syndrome and altered gut microbiota in mice lacking Toll-Like Receptor 5 publication-title: Science doi: 10.1126/science.1179721 – volume: 72 start-page: 5069 year: 2006 end-page: 5072 ident: CR51 article-title: Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.03006-05 – volume: 122 start-page: 107 year: 2005 end-page: 118 ident: CR1 article-title: An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system publication-title: Cell doi: 10.1016/j.cell.2005.05.007 – volume: 103 start-page: 732 year: 2006 end-page: 737 ident: CR16 article-title: Molecular analysis of the bacterial microbiota in the human stomach publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0506655103 – volume: 12 start-page: 1889 year: 2010 end-page: 1898 ident: CR23 article-title: Ironing out the wrinkles in the rare biosphere through improved OTU clustering publication-title: Environ. Microbiol. doi: 10.1111/j.1462-2920.2010.02193.x – volume: 60 start-page: 677 year: 2010 end-page: 690 ident: CR31 article-title: Analysis of oral microbiota in children with dental caries by PCR-DGGE and barcoded pyrosequencing publication-title: Microb. Ecol. doi: 10.1007/s00248-010-9712-8 – volume: 141 start-page: 599 year: 2011 end-page: 609 ident: CR6 article-title: The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice publication-title: Gastroenterology doi: 10.1053/j.gastro.2011.04.052 – volume: 6 start-page: e21280 year: 2011 ident: CR36 article-title: In search of an uncultured human-associated TM7 bacterium in the environment publication-title: PLoS ONE doi: 10.1371/journal.pone.0021280 – volume: 45 start-page: 3270 year: 2007 end-page: 3276 ident: CR42 article-title: Targeted PCR for detection of vaginal bacteria associated with bacterial vaginosis publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.01272-07 – volume: 73 start-page: 5261 year: 2007 end-page: 5267 ident: CR45 article-title: Naïve Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.00062-07 – volume: 77 start-page: 3846 year: 2011 end-page: 3852 ident: CR22 article-title: Generation of multi-million 16S rRNA gene libraries from complex microbial communities by assembling paired-end Illumina reads publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.02772-10 – volume: 326 start-page: 1694 year: 2009 end-page: 1697 ident: CR17 article-title: Bacterial community variation in human body habitats across space and time publication-title: Science doi: 10.1126/science.1177486 – volume: 105 start-page: 16731 year: 2008 end-page: 16736 ident: CR4 article-title: is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0804812105 – volume: 11 start-page: 247 year: 2005 end-page: 251 ident: CR28 article-title: A dynamic partnership: celebrating our gut flora publication-title: Anaerobe doi: 10.1016/j.anaerobe.2005.05.001 – volume: 87 start-page: 1016 year: 2008 end-page: 1020 ident: CR13 article-title: Pyrosequencing analysis of the oral microflora of healthy adults publication-title: J. Dent. Res. doi: 10.1177/154405910808701104 – volume: 183 start-page: 3770 year: 2001 end-page: 3783 ident: CR37 article-title: Bacterial diversity in human subgingival plaque publication-title: J. Bacteriol. doi: 10.1128/JB.183.12.3770-3783.2001 – volume: 112 start-page: 19 year: 2005 end-page: 24 ident: CR3 article-title: Periodontal disease and coronary heart disease: a reappraisal of the exposure publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.104.511998 – volume: 361 start-page: 512 year: 2003 end-page: 519 ident: CR34 article-title: Gut flora in health and disease publication-title: The Lancet doi: 10.1016/S0140-6736(03)12489-0 – volume: 38 start-page: 7 year: 2011 end-page: 16 ident: CR15 article-title: Has the use of molecular methods for the characterization of the human oral microbiome changed our understanding of the role of bacteria in the pathogenesis of periodontal disease? publication-title: J. Clin. Periodont. doi: 10.1111/j.1600-051X.2010.01679.x – volume: 105 start-page: 16731 year: 2008 ident: BFsrep00170_CR4 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0804812105 – volume: 328 start-page: 228 year: 2010 ident: BFsrep00170_CR5 publication-title: Science doi: 10.1126/science.1179721 – volume: 308 start-page: 1635 year: 2005 ident: BFsrep00170_CR27 publication-title: Science doi: 10.1126/science.1110591 – volume: 26 start-page: 2460 year: 2010 ident: BFsrep00170_CR48 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btq461 – volume: 307 start-page: 1915 year: 2005 ident: BFsrep00170_CR2 publication-title: Science doi: 10.1126/science.1104816 – volume: 122 start-page: 107 year: 2005 ident: BFsrep00170_CR1 publication-title: Cell doi: 10.1016/j.cell.2005.05.007 – volume: 457 start-page: 480 year: 2009 ident: BFsrep00170_CR12 publication-title: Nature doi: 10.1038/nature07540 – volume: 77 start-page: 3846 year: 2011 ident: BFsrep00170_CR22 publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.02772-10 – volume: 6 start-page: e21280 year: 2011 ident: BFsrep00170_CR36 publication-title: PLoS ONE doi: 10.1371/journal.pone.0021280 – volume: 102 start-page: 11070 year: 2005 ident: BFsrep00170_CR26 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0504978102 – volume: 5 start-page: e177 year: 2007 ident: BFsrep00170_CR10 publication-title: PLoS Biol. doi: 10.1371/journal.pbio.0050177 – ident: BFsrep00170_CR50 – volume: 192 start-page: 5002 year: 2010 ident: BFsrep00170_CR8 publication-title: J. Bacteriol. doi: 10.1128/JB.00542-10 – volume: 107 start-page: 11971 year: 2010 ident: BFsrep00170_CR11 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.1002601107 – volume: 324 start-page: 1190 year: 2009 ident: BFsrep00170_CR18 publication-title: Science doi: 10.1126/science.1171700 – volume: 72 start-page: 5069 year: 2006 ident: BFsrep00170_CR51 publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.03006-05 – volume: 105 start-page: 17994 year: 2008 ident: BFsrep00170_CR19 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0807920105 – volume: 103 start-page: 12115 year: 2006 ident: BFsrep00170_CR44 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0605127103 – volume: 12 start-page: 1889 year: 2010 ident: BFsrep00170_CR23 publication-title: Environ. Microbiol. doi: 10.1111/j.1462-2920.2010.02193.x – volume: 361 start-page: 512 year: 2003 ident: BFsrep00170_CR34 publication-title: The Lancet doi: 10.1016/S0140-6736(03)12489-0 – volume: 59 start-page: 695 year: 1993 ident: BFsrep00170_CR47 publication-title: Appl. Environ. Microbiol. doi: 10.1128/aem.59.3.695-700.1993 – volume: 12 start-page: R50 year: 2011 ident: BFsrep00170_CR20 publication-title: Genome Biol. doi: 10.1186/gb-2011-12-5-r50 – volume: 103 start-page: 732 year: 2006 ident: BFsrep00170_CR16 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0506655103 – volume: 183 start-page: 3770 year: 2001 ident: BFsrep00170_CR37 publication-title: J. Bacteriol. doi: 10.1128/JB.183.12.3770-3783.2001 – ident: BFsrep00170_CR54 – volume: 11 start-page: 247 year: 2005 ident: BFsrep00170_CR28 publication-title: Anaerobe doi: 10.1016/j.anaerobe.2005.05.001 – volume: 45 start-page: 3270 year: 2007 ident: BFsrep00170_CR42 publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.01272-07 – volume: 12 start-page: 259 year: 2010 ident: BFsrep00170_CR32 publication-title: Curr. Gastroenterol. Rep. doi: 10.1007/s11894-010-0111-6 – ident: BFsrep00170_CR25 doi: 10.1371/journal.pone.0015406 – volume: 82 start-page: 338 year: 2003 ident: BFsrep00170_CR39 publication-title: J. Dent. Res. doi: 10.1177/154405910308200503 – volume: 26 start-page: 1641 year: 2009 ident: BFsrep00170_CR53 publication-title: Mol. Biol. Evol. doi: 10.1093/molbev/msp077 – volume: 38 start-page: 7 year: 2011 ident: BFsrep00170_CR15 publication-title: J. Clin. Periodont. doi: 10.1111/j.1600-051X.2010.01679.x – ident: BFsrep00170_CR49 doi: 10.1007/978-0-387-98141-3 – volume: 41 start-page: 558 year: 2003 ident: BFsrep00170_CR38 publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.41.2.558-563.2003 – volume: 112 start-page: 19 year: 2005 ident: BFsrep00170_CR3 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.104.511998 – volume: 141 start-page: 599 year: 2011 ident: BFsrep00170_CR6 publication-title: Gastroenterology doi: 10.1053/j.gastro.2011.04.052 – volume: 87 start-page: 1016 year: 2008 ident: BFsrep00170_CR13 publication-title: J. Dent. Res. doi: 10.1177/154405910808701104 – volume: 101 start-page: 4250 year: 2004 ident: BFsrep00170_CR40 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0306398101 – volume: 4, start-page: 962 year: 2010 ident: BFsrep00170_CR29 publication-title: ISME J doi: 10.1038/ismej.2010.30 – volume: 326 start-page: 1694 year: 2009 ident: BFsrep00170_CR17 publication-title: Science doi: 10.1126/science.1177486 – volume: 12 start-page: 118 year: 2010 ident: BFsrep00170_CR33 publication-title: Environ. Microbiol. doi: 10.1111/j.1462-2920.2009.02051.x – volume: 22 start-page: 1658 year: 2006 ident: BFsrep00170_CR24 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btl158 – volume: 73 start-page: 5261 year: 2007 ident: BFsrep00170_CR45 publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.00062-07 – ident: BFsrep00170_CR30 doi: 10.1038/ismej.2011.85 – volume: 57 start-page: 1569 year: 2008 ident: BFsrep00170_CR41 publication-title: J. Med. Microbiol. doi: 10.1099/jmm.0.47719-0 – volume: 3 start-page: e2836 year: 2008 ident: BFsrep00170_CR21 publication-title: PLoS ONE doi: 10.1371/journal.pone.0002836 – volume: 139 start-page: 1844 year: 2010 ident: BFsrep00170_CR14 publication-title: Gastroenterology doi: 10.1053/j.gastro.2010.08.049 – volume: 104 start-page: 2927 year: 2007 ident: BFsrep00170_CR43 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0607077104 – volume: 139 start-page: 2102 year: 2010 ident: BFsrep00170_CR7 publication-title: Gastroenterology doi: 10.1053/j.gastro.2010.06.063 – volume: 7 start-page: 335 year: 2010 ident: BFsrep00170_CR52 publication-title: Nat. Methods doi: 10.1038/nmeth.f.303 – volume: 60 start-page: 677 year: 2010 ident: BFsrep00170_CR31 publication-title: Microb. Ecol. doi: 10.1007/s00248-010-9712-8 – volume: 79 start-page: 266 year: 2009 ident: BFsrep00170_CR9 publication-title: J. Microbiol. Meth. doi: 10.1016/j.mimet.2009.09.012 – volume: 464 start-page: 59 year: 2010 ident: BFsrep00170_CR35 publication-title: Nature doi: 10.1038/nature08821 – ident: BFsrep00170_CR46 – reference: 15016918 - Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4250-5 – reference: 20336157 - ISME J. 2010 Aug;4(8):962-74 – reference: 20600016 - Gastroenterology. 2010 Dec;139(6):2102-2112.e1 – reference: 20614117 - Microb Ecol. 2010 Oct;60(3):677-90 – reference: 15831718 - Science. 2005 Jun 10;308(5728):1635-8 – reference: 19018031 - J Med Microbiol. 2008 Dec;57(Pt 12):1569-76 – reference: 20532707 - Curr Gastroenterol Rep. 2010 Aug;12(4):259-62 – reference: 20709691 - Bioinformatics. 2010 Oct 1;26(19):2460-1 – reference: 20816835 - Gastroenterology. 2010 Dec;139(6):1844-1854.e1 – reference: 16009137 - Cell. 2005 Jul 15;122(1):107-18 – reference: 18665274 - PLoS One. 2008;3(7):e2836 – reference: 21460107 - Appl Environ Microbiol. 2011 Jun;77(11):3846-52 – reference: 12709498 - J Dent Res. 2003 May;82(5):338-44 – reference: 19796657 - J Microbiol Methods. 2009 Dec;79(3):266-71 – reference: 20236171 - Environ Microbiol. 2010 Jul;12(7):1889-98 – reference: 21683077 - Gastroenterology. 2011 Aug;141(2):599-609, 609.e1-3 – reference: 21323699 - J Clin Periodontol. 2011 Mar;38 Suppl 11:7-16 – reference: 17586664 - Appl Environ Microbiol. 2007 Aug;73(16):5261-7 – reference: 17594176 - PLoS Biol. 2007 Jul;5(7):e177 – reference: 11371542 - J Bacteriol. 2001 Jun;183(12):3770-83 – reference: 20203603 - Nature. 2010 Mar 4;464(7285):59-65 – reference: 19725865 - Environ Microbiol. 2010 Jan;12(1):118-23 – reference: 12574246 - J Clin Microbiol. 2003 Feb;41(2):558-63 – reference: 20566857 - Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11971-5 – reference: 16820507 - Appl Environ Microbiol. 2006 Jul;72(7):5069-72 – reference: 7683183 - Appl Environ Microbiol. 1993 Mar;59(3):695-700 – reference: 15983248 - Circulation. 2005 Jul 5;112(1):19-24 – reference: 16731699 - Bioinformatics. 2006 Jul 1;22(13):1658-9 – reference: 16033867 - Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11070-5 – reference: 17293459 - Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2927-32 – reference: 20383131 - Nat Methods. 2010 May;7(5):335-6 – reference: 16701579 - Anaerobe. 2005 Oct;11(5):247-51 – reference: 16407106 - Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):732-7 – reference: 15790844 - Science. 2005 Mar 25;307(5717):1915-20 – reference: 19043404 - Nature. 2009 Jan 22;457(7228):480-4 – reference: 19892944 - Science. 2009 Dec 18;326(5960):1694-7 – reference: 18946007 - J Dent Res. 2008 Nov;87(11):1016-20 – reference: 19004758 - Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17994-9 – reference: 21624126 - Genome Biol. 2011;12(5):R50 – reference: 20656903 - J Bacteriol. 2010 Oct;192(19):5002-17 – reference: 19478181 - Science. 2009 May 29;324(5931):1190-2 – reference: 18936492 - Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16731-6 – reference: 20203013 - Science. 2010 Apr 9;328(5975):228-31 – reference: 12583961 - Lancet. 2003 Feb 8;361(9356):512-9 – reference: 17687006 - J Clin Microbiol. 2007 Oct;45(10):3270-6 – reference: 21716308 - ISME J. 2012 Jan;6(1):46-56 – reference: 21048977 - PLoS One. 2010;5(10):e15406 – reference: 21701585 - PLoS One. 2011;6(6):e21280 – reference: 19377059 - Mol Biol Evol. 2009 Jul;26(7):1641-50 – reference: 16880384 - Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12115-20
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Snippet	We present bacterial biogeography as sampled from the human gastrointestinal tract of four healthy subjects. This study generated >32 million paired-end...
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SubjectTerms	631/114 631/158/670 631/326/171 Adult Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Biodiversity Biogeography Biopsy Colon Duodenum Female Gastrointestinal tract Gastrointestinal Tract - microbiology Humanities and Social Sciences Humans Male Metagenome - genetics Microbial activity Microflora multidisciplinary Organ Specificity Phylogeny RNA, Bacterial - genetics RNA, Ribosomal, 16S - genetics rRNA 16S Science Stomach
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Title	Bacterial biogeography of the human digestive tract
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