Influence of Oxygen Partial Pressure on Human and Mouse Myeloid Cell Line Characteristics

• Published in: Fundamental and applied toxicology Vol. 29; no. 2; pp. 287 - 293
• Main Authors: Lawrence, David A., Colinas, Robert J., Walsh, Anne C.
• Format: Journal Article
• Language: English
• Published: Boston, MA Elsevier Science (USA) 01.02.1996; San Diego, CA Academic Press; New York, NY
• Subjects: Animal cells; Animals; Biological and medical sciences; Biotechnology; Cell Division - drug effects; Establishment of new cell lines, improvement of cultural methods, mass cultures; Eukaryotic cell cultures; Fundamental and applied biological sciences. Psychology; General aspects. Methods; Glutathione - metabolism; Humans; Hydrogen Peroxide - toxicity; Leukemia, Myeloid - pathology; Leukemia, Myeloid, Acute - pathology; Medical sciences; Membrane Proteins - metabolism; Methods. Procedures. Technologies; Mice; Oxygen - metabolism; Oxygen - toxicity; Partial Pressure; Sulfhydryl Compounds - metabolism; Toxicology; Tumor Cells, Cultured; Human; Cell culture; Oxidative stress; Toxicity; Rodentia; Method; Oxidant; Myeloid cell; In vitro; Vertebrata; Mammalia; Cell line; Investigation method; Partial; Mouse; Hematopoiesis; Animal; Bone marrow; Oxygen pressure

Mouse and human cells have been reported to have different thiol characteristics (J. M. Messina and D. A. Lawrence, 1992,Int. J. Immunopharmacol.14,1221–1234). In addition, when cells are undergoing active growth, they usually have an increased thiol content. In an attempt to determine whether a mou...