Relaxin Family Member Insulin‐Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models - Maruyama, Sonomi; Wu, Chia‐Ling; Yoshida, Sumiko; Zhang, Dongying; Li, Pei‐Hsuan; Wu, Fangzhou; Parker Duffen, Jennifer; Yao, Rouan; Jardin, Blake; Adham, Ibrahim M.; Law, Ronald; Berger, Joel; et al. (Journal of the American Heart Association, 2018)
Keywords: Animals; anti‐fibrosis; anti–cardiac remodeling; Disease Models, Animal; Fibrosis; heart failure; Heart Failure - metabolism; Heart Failure - pathology; Heart Failure - physiopathology; Hypertrophy, Left Ventricular - metabolism; Hypertrophy, Left Ventricular - pathology; Hypertrophy, Left Ventricular - physiopathology; Hypertrophy, Left Ventricular - prevention & control; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins - deficiency; Intracellular Signaling Peptides and Proteins - genetics; Intracellular Signaling Peptides and Proteins - metabolism; Liver X Receptors - genetics; Liver X Receptors - metabolism; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardium - metabolism; Myocardium - pathology; Original Research; relaxin family protein; Retinoid X Receptors - genetics; Retinoid X Receptors - metabolism; Signal Transduction; Ventricular Dysfunction, Left - metabolism; Ventricular Dysfunction, Left - pathology; Ventricular Dysfunction, Left - physiopathology; Ventricular Dysfunction, Left - prevention & control; Ventricular Function, Left; Ventricular Remodeling; heart failure; anti‐fibrosis; relaxin family protein; anti–cardiac remodeling