The vascular risk associations with migraine: Relation to migraine susceptibility and progression

• Published in: Atherosclerosis Vol. 205; no. 1; pp. 15 - 22
• Main Author: Hamed, Sherifa A
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ireland Ltd 01.07.2009; Elsevier
• Subjects: Atherosclerosis (general aspects, experimental research); Biological and medical sciences; Blood and lymphatic vessels; Blood Pressure; Body Mass Index; Body Weight; C-Reactive Protein - biosynthesis; Cardiology. Vascular system; Cardiovascular; Comorbid risk factors; Comorbidity; Coronary heart disease; Disease Susceptibility; Heart; Homocysteine - blood; Humans; Inflammation; Interleukins - biosynthesis; Medical sciences; Migraine; Migraine Disorders - complications; Migraine Disorders - diagnosis; Risk; Risk Factors; Stroke - complications; Stroke - diagnosis; Tumor Necrosis Factor-alpha - biosynthesis; Vascular Diseases - complications; Vascular Diseases - diagnosis; Vascular wall injury; CRP; homocysteine; C-reactive protein; IL; migraine without aura; body mass index; Migraine; Comorbid risk factors; Inflammation; MA; TNF-α; migraine with aura; interleukin; Vascular wall injury; MoA; tumour necrosis factor-alpha; BMI; Hcy; Nervous system diseases; Cardiovascular disease; Cerebral disorder; Vascular disease; Pain; Central nervous system disease; Atherosclerosis; Risk factor; Vascular wall; Cerebrovascular disease

Abstract Migraine is a common disorder in which changes in cortical excitability, neuroinflammation and dysfunction of the vascular wall contribute to its pathophysiology. Repeated attacks of migraine over prolonged periods result in inflammatory arteriopathy of the cranial vessels. Several studies...